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  • Language: English

    Published by Springer, 2011

    3642169309 / 9783642169304

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  • Language: English

    Published by Springer 2/3/2011, 2011

    3642169309 / 9783642169304

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    Hardback or Cased Book. Condition: New. Targeting Functional Centers of the Ribosome. Book.

  • Language: English

    Published by Springer, 2013

    364226705X / 9783642267055

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  • Language: English

    Published by Springer, 2011

    3642169309 / 9783642169304

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  • Language: English

    Published by Springer, 2013

    364226705X / 9783642267055

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    Condition: New. pp. 90.

  • Language: English

    Published by Springer, 2011

    3642169309 / 9783642169304

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    Condition: New. pp. xiv + 74.

  • Language: English

    Published by Springer, 2011

    3642169309 / 9783642169304

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  • Language: English

    Published by Springer, 2011

    3642169309 / 9783642169304

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  • Language: English

    Published by Springer Verlag, 2013

    364226705X / 9783642267055

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    Paperback. Condition: Brand New. 2011 edition. 80 pages. 9.25x6.10x0.21 inches. In Stock.

  • Language: English

    Published by Springer Verlag, 2011

    3642169309 / 9783642169304

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    Hardcover. Condition: Brand New. 1st edition. 74 pages. 9.25x6.25x0.25 inches. In Stock.

  • Language: English

    Published by Springer, 2011

    3642169309 / 9783642169304

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    Buch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - This thesis describes research into the mode of function, inhibition, and evolution of the ribosomal catalytic center, the Peptidyl Transferase Center (PTC)--research that has already led to attempts at improving PTC antibiotics. The PhD candidate carried out two parallel studies. One using a combination of X-ray crystallography, biochemistry, molecular biology, and theoretical studies to obtain crystal structures of ribosomal particles with antibiotics that target the PTC, revealing the modes of action, resistance, cross-resistance and discrimination between ribosomes of eubacterial pathogens and eukaryotic hosts. In the second parallel study, the candidate synthesized a ribosomal substructure--one that may represent the minimal entity capable of catalyzing peptide bond formation--shedding light on the origin of the ribosome itself.…

  • Language: English

    Published by Springer Spektrum, 2013

    364226705X / 9783642267055

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    Taschenbuch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - This thesis describes research into the mode of function, inhibition, and evolution of the ribosomal catalytic center, the Peptidyl Transferase Center (PTC)--research that has already led to attempts at improving PTC antibiotics. The PhD candidate carried out two parallel studies. One using a combination of X-ray crystallography, biochemistry, molecular biology, and theoretical studies to obtain crystal structures of ribosomal particles with antibiotics that target the PTC, revealing the modes of action, resistance, cross-resistance and discrimination between ribosomes of eubacterial pathogens and eukaryotic hosts. In the second parallel study, the candidate synthesized a ribosomal substructure--one that may represent the minimal entity capable of catalyzing peptide bond formation--shedding light on the origin of the ribosome itself.…

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    Language: English

    Published by Springer, 2013

    364226705X / 9783642267055

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    Taschenbuch. Condition: Neu. Targeting Functional Centers of the Ribosome | Chen Davidovich | Taschenbuch | Springer Theses | xiv | Englisch | 2013 | Springer | EAN 9783642267055 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu. …

  • Language: English

    Published by J.B. Metzler, 2011

    3642169309 / 9783642169304

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    Condition: Sehr gut. Zustand: Sehr gut | Sprache: Englisch | Produktart: Bücher | This thesis describes research into the mode of function, inhibition, and evolution of the ribosomal catalytic center, the Peptidyl Transferase Center (PTC)--research that has already led to attempts at improving PTC antibiotics. The PhD candidate carried out two parallel studies. One using a combination of X-ray crystallography, biochemistry, molecular biology, and theoretical studies to obtain crystal structures of ribosomal particles with antibiotics that target the PTC, revealing the modes of action, resistance, cross-resistance and discrimination between ribosomes of eubacterial pathogens and eukaryotic hosts. In the second parallel study, the candidate synthesized a ribosomal substructure--one that may represent the minimal entity capable of catalyzing peptide bond formation--shedding light on the origin of the ribosome itself.…

  • Language: English

    Published by Springer, 2013

    364226705X / 9783642267055

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    Paperback. Condition: Like New. LIKE NEW. SHIPS FROM MULTIPLE LOCATIONS. book.

  • Language: English

    Published by Springer, 2013

    364226705X / 9783642267055

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  • Language: English

    Published by Springer, 2013

    364226705X / 9783642267055

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  • Language: English

    Published by Springer 2013-04, 2013

    364226705X / 9783642267055

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    PF. Condition: New. This item is printed on demand. Brand new book, sourced directly from publisher. Dispatch time is 6-7 days from our warehouse. Book will be sent in robust, secure packaging to ensure it reaches you securely.

  • Language: English

    Published by Springer Berlin Heidelberg Feb 2011, 2011

    3642169309 / 9783642169304

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    Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This thesis describes research into the mode of function, inhibition, and evolution of the ribosomal catalytic center, the Peptidyl Transferase Center (PTC)--research that has already led to attempts at improving PTC antibiotics. The PhD candidate carried out two parallel studies. One using a combination of X-ray crystallography, biochemistry, molecular biology, and theoretical studies to obtain crystal structures of ribosomal particles with antibiotics that target the PTC, revealing the modes of action, resistance, cross-resistance and discrimination between ribosomes of eubacterial pathogens and eukaryotic hosts. In the second parallel study, the candidate synthesized a ribosomal substructure--one that may represent the minimal entity capable of catalyzing peptide bond formation--shedding light on the origin of the ribosome itself. 88 pp. Englisch.…

  • Language: English

    Published by Springer Berlin Heidelberg Apr 2013, 2013

    364226705X / 9783642267055

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    Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This thesis describes research into the mode of function, inhibition, and evolution of the ribosomal catalytic center, the Peptidyl Transferase Center (PTC)--research that has already led to attempts at improving PTC antibiotics. The PhD candidate carried out two parallel studies. One using a combination of X-ray crystallography, biochemistry, molecular biology, and theoretical studies to obtain crystal structures of ribosomal particles with antibiotics that target the PTC, revealing the modes of action, resistance, cross-resistance and discrimination between ribosomes of eubacterial pathogens and eukaryotic hosts. In the second parallel study, the candidate synthesized a ribosomal substructure--one that may represent the minimal entity capable of catalyzing peptide bond formation--shedding light on the origin of the ribosome itself. 88 pp. Englisch.…

  • Language: English

    Published by Springer, 2013

    364226705X / 9783642267055

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    Condition: New. Print on Demand pp. 90.

  • Language: English

    Published by Springer, 2011

    3642169309 / 9783642169304

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    Condition: New. Print on Demand pp. xiv + 74.

  • Language: English

    Published by Springer, 2011

    3642169309 / 9783642169304

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    Condition: New. PRINT ON DEMAND pp. xiv + 74.

  • Language: English

    Published by Springer, 2013

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  • Language: English

    Published by Springer Berlin Heidelberg, 2013

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    Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Nominated by the Weizmann Institute, Israel for a Springer Theses PrizeThis research has already led to attempts to improve PTC antibioticsBased on these findings further research into designing a functional construct mimicking a functional.…

  • Language: English

    Published by Springer Berlin Heidelberg, 2011

    3642169309 / 9783642169304

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    Gebunden. Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Nominated by the Weizmann Institute, Israel for a Springer Theses PrizeThis research has already led to attempts to improve PTC antibioticsBased on these findings further research into designing a functional construct mimicking a functional.…

  • Language: English

    Published by Springer, Springer Apr 2013, 2013

    364226705X / 9783642267055

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    Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This thesis describes research into the mode of function, inhibition, and evolution of the ribosomal catalytic center, the Peptidyl Transferase Center (PTC)--research that has already led to attempts at improving PTC antibiotics. The PhD candidate carried out two parallel studies. One using a combination of X-ray crystallography, biochemistry, molecular biology, and theoretical studies to obtain crystal structures of ribosomal particles with antibiotics that target the PTC, revealing the modes of action, resistance, cross-resistance and discrimination between ribosomes of eubacterial pathogens and eukaryotic hosts. In the second parallel study, the candidate synthesized a ribosomal substructure--one that may represent the minimal entity capable of catalyzing peptide bond formation--shedding light on the origin of the ribosome itself.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 88 pp. Englisch.…

  • Language: English

    Published by Springer, Springer Feb 2011, 2011

    3642169309 / 9783642169304

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    Buch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This thesis describes research into the mode of function, inhibition, and evolution of the ribosomal catalytic center, the Peptidyl Transferase Center (PTC)--research that has already led to attempts at improving PTC antibiotics. The PhD candidate carried out two parallel studies. One using a combination of X-ray crystallography, biochemistry, molecular biology, and theoretical studies to obtain crystal structures of ribosomal particles with antibiotics that target the PTC, revealing the modes of action, resistance, cross-resistance and discrimination between ribosomes of eubacterial pathogens and eukaryotic hosts. In the second parallel study, the candidate synthesized a ribosomal substructure--one that may represent the minimal entity capable of catalyzing peptide bond formation--shedding light on the origin of the ribosome itself.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 88 pp. Englisch.…

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