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Evan R Simpson (14 results)
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Condition: As New. Unread book in perfect condition.
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paperback. Condition: Good. Ex-library book with typical stickers and stampings. Priority Mail is available on this item. No international shipping.
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Obesity and Breast Cancer : The Role of Dysregulated Estrogen Metabolism
Seller: GreatBookPricesUK, Woodford Green, United Kingdom
Seller rating 5 out of 5 stars
US$ 67.06
US$ 19.80 shipping
Ships from United Kingdom to U.S.A.Quantity: Over 20 available
Add to basketCondition: New.
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Obesity and Breast Cancer : The Role of Dysregulated Estrogen Metabolism
Seller: GreatBookPricesUK, Woodford Green, United Kingdom
Seller rating 5 out of 5 stars
US$ 76.05
US$ 19.80 shipping
Ships from United Kingdom to U.S.A.Quantity: Over 20 available
Add to basketCondition: As New. Unread book in perfect condition.
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Condition: New. pp. 68.
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US$ 87.16
US$ 13.20 shipping
Ships from United Kingdom to U.S.A.Quantity: 2 available
Add to basketPaperback. Condition: Brand New. 1st edition. 56 pages. 9.00x6.00x0.25 inches. In Stock.
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Kartoniert / Broschiert. Condition: New.
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Australian Poetry 1964 - First Edition
Published by Sydney: Angus and Robertson, 1964
Seller: Benedict Wilson Books, Folkestone, KENT, United Kingdom
Seller rating 5 out of 5 stars
First Edition
US$ 40.78
US$ 26.40 shipping
Ships from United Kingdom to U.S.A.Quantity: 1 available
Add to basketHardcover. Condition: Near Fine. Dust Jacket Included. 1st Edition. FIRST EDITION, first printing. Octavo (20 x 14cm), pp.x; 94. Publisher's green cloth titles in gilt to spine. Dust-jacket with printed price of 15s. to front flap. A little dustiness to edges, dust-jacket lightly handled, toned to spine. Near fine.
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Obesity and Breast Cancer : The Role of Dysregulated Estrogen Metabolism
Language: English
Published by Springer New York, Springer US, 2013
ISBN 10: 1489980016 ISBN 13: 9781489980014
Taschenbuch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - Obesity is a risk factor for breast cancer in older women. A number of adipose-derived and obesity-related factors have been shown to affect tumour cell growth. These include adipokines, insulin, IGF-1 and oestrogens. The majority of obesity-related postmenopausal breast cancers are oestrogen-dependent. Since the ovaries no longer produce oestrogens after menopause, and that circulating levels are negligible, it is evident that it is the oestrogens produced locally within the breast adipose that are responsible for the increased growth of breast cancer cells. Aromatase is the enzyme that converts androgens into oestrogens and its regulation is dependent on the activity of a number of tissue-specific promoters. Targeting oestrogen biosynthesis in obesity may be useful for the prevention of breast cancer. Aromatase inhibitors are efficacious at treating postmenopausal breast cancer and recent studies suggest that they may also be useful in the prevention setting. However, these compounds inhibit the catalytic activity of aromatase and as a consequence lead to a number of undesirable side-effects, including arthralgia and possible cognitive defects due to inhibition of aromatase in the bone and brain, respectively. Novel therapies, such as those employed to treat obesity-associated disease, including anti-diabetics, may prove successful at inhibiting aromatase specifically within the breast. This SpringerBrief will explore all of these issues in depth and the authors are in a unique position to write about this topic, having extensive experience in the field of aromatase research.
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Obesity and Breast Cancer
Language: English
Published by Springer New York Nov 2013, 2013
ISBN 10: 1489980016 ISBN 13: 9781489980014
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
Seller rating 5 out of 5 stars
Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Obesity is a risk factor for breast cancer in older women. A number of adipose-derived and obesity-related factors have been shown to affect tumour cell growth. These include adipokines, insulin, IGF-1 and oestrogens. The majority of obesity-related postmenopausal breast cancers are oestrogen-dependent. Since the ovaries no longer produce oestrogens after menopause, and that circulating levels are negligible, it is evident that it is the oestrogens produced locally within the breast adipose that are responsible for the increased growth of breast cancer cells. Aromatase is the enzyme that converts androgens into oestrogens and its regulation is dependent on the activity of a number of tissue-specific promoters. Targeting oestrogen biosynthesis in obesity may be useful for the prevention of breast cancer. Aromatase inhibitors are efficacious at treating postmenopausal breast cancer and recent studies suggest that they may also be useful in the prevention setting. However, these compounds inhibit the catalytic activity of aromatase and as a consequence lead to a number of undesirable side-effects, including arthralgia and possible cognitive defects due to inhibition of aromatase in the bone and brain, respectively. Novel therapies, such as those employed to treat obesity-associated disease, including anti-diabetics, may prove successful at inhibiting aromatase specifically within the breast. This SpringerBrief will explore all of these issues in depth and the authors are in a unique position to write about this topic, having extensive experience in the field of aromatase research. 68 pp. Englisch.
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Condition: New. Print on Demand pp. 68 9 Illus. (7 Col.).
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Condition: New. PRINT ON DEMAND pp. 68.
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US$ 108.27
US$ 55.81 shipping
Ships from Germany to U.S.A.Quantity: Over 20 available
Add to basketCondition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. First comprehensive overview on the different aromatase inhibitorsIncludes preclinical and clinical studiesGives outlook on future uses of aromatase inhibitorsInternational authorshipThis book provides the first comprehens.
