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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Beschreibung The recent rise of bio-succinic acid as an industrial platform chemical has brought the rumen bacterium Basfia succiniciproducens, a natural producer of this organic acid, into the focus of research. This work investigated the potential of B. succiniciproducens for the production of carbon-three chemicals from sugars. Beside the optimization of improved genetic tools, the C3 chemicals alanine, ¿-alanine and 3-hydroxypropionate (3-HP) were targeted. A new alanine producer, B. succiniciproducens ALA-1, exhibited good performance in the bioprocess. The next step demonstrated the proof-of-concept for ¿-alanine synthesis using the heterologous expression of aspartate 1 decarboxylase genes from Corynebacterium glutamicum or Vibrio natriegens. The expression of two additional genes enabled the de novo synthesis of up to 100 mg L-1 3-HP from glucose. 144 pp. Englisch.
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Published by Cuvillier, Cuvillier Dez 2018, 2018
ISBN 10: 3736999135 ISBN 13: 9783736999138
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Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Beschreibung The recent rise of bio-succinic acid as an industrial platform chemical has brought the rumen bacterium Basfia succiniciproducens, a natural producer of this organic acid, into the focus of research. This work investigated the potential of B. succiniciproducens for the production of carbon-three chemicals from sugars. Beside the optimization of improved genetic tools, the C3 chemicals alanine, ¿-alanine and 3-hydroxypropionate (3-HP) were targeted. A new alanine producer, B. succiniciproducens ALA-1, exhibited good performance in the bioprocess. The next step demonstrated the proof-of-concept for ¿-alanine synthesis using the heterologous expression of aspartate 1 decarboxylase genes from Corynebacterium glutamicum or Vibrio natriegens. The expression of two additional genes enabled the de novo synthesis of up to 100 mg L-1 3-HP from glucose.Cuvillier Verlag, Nonnenstieg 8, 37075 Göttingen 144 pp. Englisch.
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Published by Cuvillier, Cuvillier, 2018
ISBN 10: 3736999135 ISBN 13: 9783736999138
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Taschenbuch. Condition: Neu. Metabolic engineering of Basfia succiniciproducens for the production of carbon-three compounds (Band 7) | Jonathan Thomas Fabarius | Taschenbuch | Hochschulschriften - Institut für Biotechnologie, Universität des Saarlandes | 144 S. | Englisch | 2018 | Cuvillier | EAN 9783736999138 | Verantwortliche Person für die EU: BoD - Books on Demand, In de Tarpen 42, 22848 Norderstedt, info[at]bod[dot]de | Anbieter: preigu Print on Demand.