G D Ledney (31 results)
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Taschenbuch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - United States government. Defense Nuclear firms, Hoffman-LaRoche and Ciba-Geigy, and by Agency, Armed Forces Radiobiology Research In the American firm, Travenol. stitute. SIEGMUNDJ. BAUM Furthermore, we greatly appreciate the gener G. DAVID LEDNEY… ous financial support by the Swiss pharmaceutical vi Xlll List of Contributors Part I Regulation of Stem Cell Proliferation L. G. Lajtha 1 Regulation of Stem Cell Proliferation 3 L. G. Lajtha and E. G. Wright Introduction 3 Experimental Evidence 3 Summary 7 References 7 Contents 2 Surface Antigens of Hemopoietic Stem Cells: The Expression of BAS, Thy-1, and H-2 Antigens on CFU-s 9 Ger van den Engh, Jim Russell, and Diane de Cicco Introduction 9 Materials and Methods 10 Results 11 Discussion 13 Summary 14 Acknowledgments 14 References 15 3 The Regulation of Hemopoiesis: Effect of Thymosin or Thymocytes in a Diffusion Chamber 17 S. J. Sharkis, A. Ahmed, L. L. Sensenbrenner, W. W. Jedrzejczak, A. L. Goldstein, and K. W. Sell Introduction 17 Materials and Methods 17 Results 18 Discussion 20 Summary 21 Acknowledgments 21 References 21 4 Anti-CFU-s Activity of Rabbit Anti mouse Brain Serum: Mechanism of Action 23 Solomon S. Adler, Richard D. Kuznetsky, and Frank E. Trobaugh, Jr. Introduction 23 Materials and Methods 23 Results 26 Discussion 29 Summary 31 Acknowledgments 31 References 31 vii Contents Part II Ralph van Furth, Theo J. L. M. Goud, and Physiology of Committed Dick van Waarde Stem Cells 33 Introduction 65 D.
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Taschenbuch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - It is perhaps not too much of an exaggeration to claim that experimental hematology as it flourishes today originated largely from the pioneering attempts to protect lethally radiated animals (1) by shielding of hemopoietic tissues by L. O. Jacobso…n (9), and (2) by treatment with bone marrow suspensions by E. Lorenz and his col laborators (12). The site chosen for this annual meeting of the International Society for Experi mental Hematology is given a special historic sig nificance by the fact that it was 25 years ago that the first publication on this subject by Lorenz ap peared from his laboratory at the National Insti tutes of Health. Lorenz's discovery marked the beginning of a period which lasted until 1956, during which the protection afforded by hemopoietic cell suspensions was confirmed by many. This soon led to an intensive scientific de bate on the mechanism of this protective effect: was it due to a humoral factor produced and pro vided by the bone marrow-as Lorenz The Appearance of postulated-or to transplantation and subsequent proliferation of hemop- etic cells This question was defini- 1 the Multipotential tively answered in 1956 by evidence from three different laboratories (7, 15, 26), which demonstrated the origin of the cells Hemopoietic in the repopulated tissues using a variety of cellu lar and immunologic markers. By the same token, these contributions marked the birth of radiation Stem Cell chimeras.
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Published by Springer New York, Chapman And Hall/CRC Okt 2011, 2011
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -United States government. Defense Nuclear firms, Hoffman-LaRoche and Ciba-Geigy, and by Agency, Armed Forces Radiobiology Research In the American firm, Travenol. stitute. SIEGMUNDJ. BAUM Furthermore, we greatly appreciate the gener… G. DAVID LEDNEY ous financial support by the Swiss pharmaceutical vi Xlll List of Contributors Part I Regulation of Stem Cell Proliferation L. G. Lajtha 1 Regulation of Stem Cell Proliferation 3 L. G. Lajtha and E. G. Wright Introduction 3 Experimental Evidence 3 Summary 7 References 7 Contents 2 Surface Antigens of Hemopoietic Stem Cells: The Expression of BAS, Thy-1, and H-2 Antigens on CFU-s 9 Ger van den Engh, Jim Russell, and Diane de Cicco Introduction 9 Materials and Methods 10 Results 11 Discussion 13 Summary 14 Acknowledgments 14 References 15 3 The Regulation of Hemopoiesis: Effect of Thymosin or Thymocytes in a Diffusion Chamber 17 S. J. Sharkis, A. Ahmed, L. L. Sensenbrenner, W. W. Jedrzejczak, A. L. Goldstein, and K. W. Sell Introduction 17 Materials and Methods 17 Results 18 Discussion 20 Summary 21 Acknowledgments 21 References 21 4 Anti-CFU-s Activity of Rabbit Anti mouse Brain Serum: Mechanism of Action 23 Solomon S. Adler, Richard D. Kuznetsky, and Frank E. Trobaugh, Jr. Introduction 23 Materials and Methods 23 Results 26 Discussion 29 Summary 31 Acknowledgments 31 References 31 vii Contents Part II Ralph van Furth, Theo J. L. M. Goud, and Physiology of Committed Dick van Waarde Stem Cells 33 Introduction 65 D. 276 pp. Englisch.
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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. I. Characterization of the Multipotential Stem Cell (CFU-s).- 1. The Appearance of the Multipotential Hemopoietic Stem Cell.- The spleen colony assay of rat HSC.- Concentration and identification of rat HSC.- Summary.…- Acknowledgments.- References.- 2. An I.
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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. I Studies of Hemopoietic Stem Cells.- 1 Alterations Induced in Murine Hemopoietic Stem Cells Following a Single Injection of Corynebacterium parvum.- Materials and Methods.- Results.- Discussion.- Summary.- References….- 2 Growth Control of Hemopoietic Colon.
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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. I Regulation of Stem Cell Proliferation.- 1 Regulation of Stem Cell Proliferation.- Experimental Evidence.- Summary.- References.- 2 Surface Antigens of Hemopoietic Stem Cells: The Expression of BAS, Thy-1, and H-2 An…tigens on CFU-s.- Materials and Methods.
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware 288 pp. Englisch.
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -It is perhaps not too much of an exaggeration to claim that experimental hematology as it flourishes today originated largely from the pioneering attempts to protect lethally radiated animals (1) by shielding of hemopoietic tissues…by L. O. Jacobson (9), and (2) by treatment with bone marrow suspensions by E. Lorenz and his col laborators (12). The site chosen for this annual meeting of the International Society for Experi mental Hematology is given a special historic sig nificance by the fact that it was 25 years ago that the first publication on this subject by Lorenz ap peared from his laboratory at the National Insti tutes of Health. Lorenz's discovery marked the beginning of a period which lasted until 1956, during which the protection afforded by hemopoietic cell suspensions was confirmed by many. This soon led to an intensive scientific de bate on the mechanism of this protective effect: was it due to a humoral factor produced and pro vided by the bone marrow-as Lorenz The Appearance of postulated-or to transplantation and subsequent proliferation of hemop- etic cells This question was defini- 1 the Multipotential tively answered in 1956 by evidence from three different laboratories (7, 15, 26), which demonstrated the origin of the cells Hemopoietic in the repopulated tissues using a variety of cellu lar and immunologic markers. By the same token, these contributions marked the birth of radiation Stem Cell chimeras. 272 pp. Englisch.
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Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -I. Characterization of the Multipotential Stem Cell (CFU-s).- 1. The Appearance of the Multipotential Hemopoietic Stem Cell.- 2. An Immunologic Approach to Cell Cycle Analysis of the Stem Cell.- 3. Physical Separation of the Cycling and… Noncycling Compartments of Murine Hemopoietic Stem Cells.- 4. Characterization of Bone Marrow and Lymph Node Repopulating Cells by Transplanting Mononuclear Cells into Radiated Dogs.- II. Humoral and Cellular Control Agents.- 5. Concepts and Observations on the Regulation of Granulocyte Production.- 6. The Regulatory Role of the Macrophage in Normal and Neoplastic Hemopoiesis.- 7. Humoral Regulation of Eosinophil Granulocytopoiesis.- 8. Studies of the Erythroid Inductive Microenvironment in Vitro.- 9. In Vivo Colony Forming Unit Population Sizes in Hypertransfused Sl/Sld Mice.- III. Physiology of Committed Stem Cells (CFU-e and CFU-m).- 10. Recognition of Hemopoietic Progenitors.- 11. Relationships between Early Hemopoietic Progenitor Cells Determined by Correlation Analysis of Their Numbers in Individual Spleen Colonies.- 12. Some Characteristics of in Vitro Erythroid Colony and Burst-Forming Units.- 13. Colony-Forming Unit, Megakaryocyte (CFU-m): Its Use in Elucidating the Kinetics and Humoral Control of the Megakaryocytic Committed Progenitor Cell Compartment.- IV. Physiology of Committed Stem Cells (CFU-c).- 14. Negative and Positive Feedback Control of the Committed Granulocytic Stem Cell Compartment.- 15. Colony-Stimulating Factor and the Differentiation of Granulocytes and Macrophages.- 16. Characteristics of the in Vitro Monocyte-Macrophage Colony-Forming Cells Detected within Mouse Thymus and Lymph Nodes.- 17. Physical Characterization of a Subpopulation of Granulocyte/Monocyte Progenitor Cells (CFU-c).- 18. Cell-Factor Interaction in Populations of Normal and Leukemic Blood Cells.- V. Bone Marrow Transplantation Immunology.- 19. Bone Marrow Transplantation Immunology.- 20. Modulation of Graft-versus-Host (GvH) Disease in the Rat; Effect of Hydroxyurea on the Mixed Lymphocyte Reaction and Graft-versus-Host Reactivity.- 21. Mechanism of Donor to Host Tolerance in Rat Bone Marrow Chimeras.- 22. Effects of a Cell-Free Helper Factor(s) on the Kinetics of T-Cell Responses to Histocompatibility Antigens.- VI. Experimental Models of Clinical Conditions in Hematology.- 23. The E(AkR)-Leukemia as Murine Model of Human Acute Lymphoid Leukemia for Immunotherapy Trials.- 24. Experimental Chemotherapy: A Rat Model for Human Acute Myeloid Leukemia.- 25. Serum Colony Stimulating Factor: A Marker for Graft-versus-Host Disease in Humans.- 26. Changes in Human Bone Marrow Colony-Forming Cells following Chemotherapy Using an Agar Diffusion-Chamber Technique.- 27. Graft-versus-Leukemia, Donor Selection for Adoptive Immunotherapy in Mice.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 272 pp. Englisch.
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Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 288 pp. Englisch.
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Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -I Regulation of Stem Cell Proliferation.- 1 Regulation of Stem Cell Proliferation.- 2 Surface Antigens of Hemopoietic Stem Cells: The Expression of BAS, Thy-1, and H-2 Antigens on CFU-s.- 3 The Regulation of Hemopoiesis: Effect of Thymo…sin or Thymocytes in a Diffusion Chamber.- 4 Anti-CFU-s Activity of Rabbit Anti-mouse Brain Serum: Mechanism of Action.- II Physiology of Committed Stem Cells.- 5 The Control of Neutrophil and Macrophage Production at the Progenitor Cell Level.- 6 The Mononuclear Phagocyte and Its Regulatory Interactions in Hemopoiesis.- 7 Analysis of the Cells Forming Pure and Mixed Erythroid Colonies in Agar after Stimulation by Pokeweed Mitogen-stimulated, Spleen-conditioned Medium.- 8 Current Studies on the Proliferation of Cells of the Mononuclear Phagocyte System.- 9 Colony-forming Cells in the Thymus and Mesenteric Lymph Nodes of Mice Engrafted with Lewis Lung Carcinoma Cells.- III Transplantation Immunology.- 10 Expression of Normal and Leukemia associated Antigens on Blood Cell Malignancies.- 11 Leukocyte Transfusions for the Modification of Host-versus-graft Reactions in Dogs.- 12 Minor Histocompatibility Systems in Dogs.- 13 The Role of Mononuclear Phagocytes in the Defense against Infections and Malignancies.- 14 Enhancement of Immunological Responses by Methotrexate Pretreatment as a Result of an Eventual Elimination of Suppressor Cells.- 15 Syngeneic and Autologous Bone Marrow Transplantation after Noncurative Chemotherapy with AAFC, DMM, and Cyclophosphamide in Tumor-bearing Mice.- IV Therapeutic Approaches to Aplastic Anemia.- 16 On the Pathogenesis and Treatment of Aplastic Anemia.- 17 Engraftment of HLA Identical Marrow in Treatment of Severe Aplastic Anemia: Results of 110 Consecutive Transplants.- 18 The Role of Cyclophosphamide and Total-body Irradiation in Marrow Transplantation for Severe Aplastic Anemia.- 19 Histocompatibility Testing for Bone- George W. Santos and Saul J. Sharkis marrow Grafting.- 20 Recent Developments in Histocompatibility Testing in Bone Marrow Transplantation.- 21 Transplantation of Lymphoid Cells in Patients with Severe Combined Immunodeficiency (SCID).- V Treatment of Leukemia.- 22 Experience with Syngeneic Marrow Transplantation in Brown-Norway and Wistar-Furth Rat Models of Acute Myelogenous Leukemia.- 23 Marrow Transplantation for Acute Leukemia.- 24 Use of Decontamination and a Protected Environment to Prevent Secondary Disease following Adoptive Immunotherapy of Acute Leukemia in Mice.- 25 Procurement of Proliferative and Quiescent Acute Leukemia Cells by Centrifugal Elutriation.- VI Advances in Experimental Hematology.- 26 Cellular Requirements for Induction of Colony-stimulating Factor in Lymphoid Cell Cultures Stimulated by T- and B-Cell Mitogens.- 27 Serum Blocking Factor-mediated Decrease of T-Cell Immunity Induced by Soluble Histocompatibility Antigens (SHA); Similar Effects of Antibody-free SHA-raised and Hemagglutinating enhancing Sera.- 28 Ultrastructural Analysis of Preserved Dog Granulocytes.- 29 Relationship between Colony-forming Cells in Diffusion Chambers in Vivo (CFU-d) and Colony-forming Cells in Agar in Vitro (CFU-c): 22j Physical Separation and Kinetics in Culture.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 276 pp. Englisch.
