Greally John (46 results)

Hardcover. Condition: New. This is a new book. All orders ship by next business day! We are a small company and very thankful for your business!

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Hardback or Cased Book. Condition: New. Epigenetics: History, Molecules, and Diseases. Book.

Condition: As New. Unread book in perfect condition.

Hardback. Condition: VG+. Dust Jacket Condition: nrVG DW. David Till (DW) (illustrator). 1st Edition. Clean tight book but some edge spotting. DW has minro edge wear.

Hardback. Condition: New.

Condition: As New. Unread book in perfect condition.

Hardback. Condition: New.

Condition: New.

first edition, green cloth with gilt to spine, 174pp,NF with v sl foxing to top edge, in VG+ d/w(v sl sunned soiled with v sl foxing to flaps).

Hardcover. Condition: Brand New. 412 pages. 9.00x6.00x9.00 inches. In Stock.

Hardcover. Condition: Fine. Dust Jacket Condition: Fine. First edition. Fine, with a small stain to the foredge, in a fine dustwrapper with light soiling and little edgewear. A Maltese physics teacher decides to leave his native island in search of the ideal wife.

Hardback. Condition: New.

Hardback. Condition: New.

Condition: Good. Your purchase helps support Sri Lankan Children's Charity 'The Rainbow Centre'. Ex-library, so some stamps and wear, but in good overall condition. Our donations to The Rainbow Centre have helped provide an education and a safe haven to hundreds of children who live in appalling conditions.

Hardcover. Condition: Good. Ex library book. Hardback, usual markings. Clean copy, sound binding. Quick dispatch from UK seller.

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Condition: Sehr gut. Zustand: Sehr gut | Seiten: 456 | Sprache: Englisch | Produktart: Bücher | Epigenetic modifications act on DNA and its packaging proteins, the histones, to regulate genome function. Manifest as the heritable methylation of DNA and as post-translational histone modifications, these molecular flags influence the architecture and integrity of the chromosome, the accessibility of DNA to gene regulatory components and the ability of chromatin to interact within nuclear complexes. While a multicellular individual has only one genome, it has multiple epigenomes reflecting the diversity of cell types and their properties at different times of life; in health and in disease. Relationships are emerging between the underlying DNA sequence and dynamic epigenetic states and their consequences,such as the role of RNA interference and non-coding RNA. These integrated approaches go hand-in-hand with studies describing the genomic locations of epigenetic modifications in different cell types at different times.The excitement and curiosity surrounding epigenomics is driven by a growing community of researchers in a burgeoning field and the development of new technologies built on the backbone of genome sequencing projects. Research has shown that the adaptability and vulnerability of epigenetic states has profound effects on natural variation, the response of the genome to its environment and on health and disease.The aim of this volume is not to describe epigenomes, but rather to explore how understanding epigenomes tells us more about how biological systems work and the challenges and approaches taken to accomplish this. These contributions have attempted to integrate epigenomics into our understanding of genomes in wider context, and to communicate some of the wonders of epigenetics illustrated through examples across the biological spectrum.

Taschenbuch. Condition: Neu. Epigenomics | Anne C. Ferguson-Smith (u. a.) | Taschenbuch | xiv | Englisch | 2014 | Springer | EAN 9789400789548 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.

Condition: Hervorragend. Zustand: Hervorragend | Seiten: 456 | Sprache: Englisch | Produktart: Bücher | Epigenetic modifications act on DNA and its packaging proteins, the histones, to regulate genome function. Manifest as the heritable methylation of DNA and as post-translational histone modifications, these molecular flags influence the architecture and integrity of the chromosome, the accessibility of DNA to gene regulatory components and the ability of chromatin to interact within nuclear complexes. While a multicellular individual has only one genome, it has multiple epigenomes reflecting the diversity of cell types and their properties at different times of life; in health and in disease. Relationships are emerging between the underlying DNA sequence and dynamic epigenetic states and their consequences,such as the role of RNA interference and non-coding RNA. These integrated approaches go hand-in-hand with studies describing the genomic locations of epigenetic modifications in different cell types at different times.The excitement and curiosity surrounding epigenomics is driven by a growing community of researchers in a burgeoning field and the development of new technologies built on the backbone of genome sequencing projects. Research has shown that the adaptability and vulnerability of epigenetic states has profound effects on natural variation, the response of the genome to its environment and on health and disease.The aim of this volume is not to describe epigenomes, but rather to explore how understanding epigenomes tells us more about how biological systems work and the challenges and approaches taken to accomplish this. These contributions have attempted to integrate epigenomics into our understanding of genomes in wider context, and to communicate some of the wonders of epigenetics illustrated through examples across the biological spectrum.

Condition: New. pp. 438.

Taschenbuch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - Epigenetic modifications act on DNA and its packaging proteins, the histones, to regulate genome function. Manifest as the heritable methylation of DNA and as post-translational histone modifications, these molecular flags influence the architecture and integrity of the chromosome, the accessibility of DNA to gene regulatory components and the ability of chromatin to interact within nuclear complexes. While a multicellular individual has only one genome, it has multiple epigenomes reflecting the diversity of cell types and their properties at different times of life; in health and in disease. Relationships are emerging between the underlying DNA sequence and dynamic epigenetic states and their consequences,such as the role of RNA interference and non-coding RNA. These integrated approaches go hand-in-hand with studies describing the genomic locations of epigenetic modifications in different cell types at different times.The excitement and curiosity surrounding epigenomics is driven by a growing community of researchers in a burgeoning field and the development of new technologies built on the backbone of genome sequencing projects. Research has shown that the adaptability and vulnerability of epigenetic states has profound effects on natural variation, the response of the genome to its environment and on health and disease.The aim of this volume is not to describe epigenomes, but rather to explore how understanding epigenomes tells us more about how biological systems work and the challenges and approaches taken to accomplish this. These contributions have attempted to integrate epigenomics into our understanding of genomes in wider context, and to communicate some of the wonders of epigenetics illustrated through examples across the biological spectrum.

Condition: New. pp. 456.

Buch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - Epigenetic modifications act on DNA and its packaging proteins, the histones, to regulate genome function. Manifest as the heritable methylation of DNA and as post-translational histone modifications, these molecular flags influence the architecture and integrity of the chromosome, the accessibility of DNA to gene regulatory components and the ability of chromatin to interact within nuclear complexes. While a multicellular individual has only one genome, it has multiple epigenomes reflecting the diversity of cell types and their properties at different times of life; in health and in disease. Relationships are emerging between the underlying DNA sequence and dynamic epigenetic states and their consequences,such as the role of RNA interference and non-coding RNA. These integrated approaches go hand-in-hand with studies describing the genomic locations of epigenetic modifications in different cell types at different times.The excitement and curiosity surrounding epigenomics is driven by a growing community of researchers in a burgeoning field and the development of new technologies built on the backbone of genome sequencing projects. Research has shown that the adaptability and vulnerability of epigenetic states has profound effects on natural variation, the response of the genome to its environment and on health and disease.The aim of this volume is not to describe epigenomes, but rather to explore how understanding epigenomes tells us more about how biological systems work and the challenges and approaches taken to accomplish this. These contributions have attempted to integrate epigenomics into our understanding of genomes in wider context, and to communicate some of the wonders of epigenetics illustrated through examples across the biological spectrum.

Hardcover. Condition: Brand New. 1st edition. 438 pages. 9.25x6.25x0.75 inches. In Stock.

Hardcover. Condition: new. Hardcover. The concept of epigenetics is fascinating, confusing, and often misapplied. Yet it offers the tantalizing promise of explaining how cells with the same DNA acquire different identities and behaviors as they develop, how traits may possibly be passed through generations without changes to DNA sequence, and how environmental exposure may influence biological functions and ultimately human health.In this book's wide-ranging, iconoclastic exploration of the topic, John Greally traces the evolution of the concept of epigenetics from its historical roots in embryology to today's sprawling landscape of molecular definitions, genomic technologies, and disease hypotheses. He shows how epigenetics has captivated scientists, clinicians, and the public-and why caution is needed to avoid overinterpretation and pseudoscience.Written with clarity and authority, Epigenetics rejects simplistic answers and exaggerated claims to refocus the reader on what matters most: how cells establish and preserve identity and how this understanding translates into insights that are meaningful for human health.Essential reading for scientists, clinicians, students, and anyone curious about biology, this book is a guide to what epigenetics is, and is not. This item is printed on demand. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.

Condition: New. Print on Demand.

Condition: New. Print on Demand.

Condition: New. PRINT ON DEMAND.