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Elucidating the Epistatic Network of Cardiac and Skeletal Myogenesis
Language: English
Published by VDM Verlag Dr. Müller, 2008
ISBN 10: 3836489805 ISBN 13: 9783836489805
Taschenbuch. Condition: Neu. Elucidating the Epistatic Network of Cardiac and Skeletal Myogenesis | Taschenbuch | Englisch | VDM Verlag Dr. Müller | EAN 9783836489805 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu.
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Elucidating the Epistatic Network of Cardiac and Skeletal Myogenesis
Language: English
Published by VDM Verlag Dr. Müller, 2008
ISBN 10: 3836489805 ISBN 13: 9783836489805
Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The striated muscle forming regions in the vertebrate embryo respond to extra-cellular signals emitted from surrounding structures. Subsequently, genetic programs are activated in these tissues; ultimately forming cardiac or skeletal myocytes. P19 are embryonal carcinoma cells that can differentiate into beating myocardium and multi-nucleated skeletal myotubes that are biochemically and physiologically similar to in vivo tissues. MyoD (a member of the Myogenic Regulatory Factors (MRFs)), Sonic Hedgehog (Shh), Gli2 and Meox1 play roles in the commitment of cells into the skeletal muscle lineage. To further define their roles in regulating skeletal myogenesis, MyoD, Shh, Gli2 and Meox1 were examined in the context of differentiating P19 cells.
