Peter L M Jansen (33 results)

Condition: New. pp. xiii + 366.

Taschenbuch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - membrane contamination and thus could then be used to study transport function when pre pared as membrane vesicles. These approaches defined a number of transport functions in the plasma membranes of hepatocyres and ultimately led to the recognition that bile salts and 3 25 other solutes were transported into bile largely by ATP dependent transport mechanisms.2 - The advent ofmolecular cloning techniques and cellular expression systems rapidly acceler ated progress in this field and led to the molecular characterization ofmost ofthe major mem brane transport proteins that determine both the hepatic uptake of organic solutes as well as bile salt dependent and bile salt independent canalicular excretion. Overview of the Molecular Mechanisms of Bile Formation The major transporters that determine bile formation are illustrated in Figure 1 and are discussed in greater detail in the subsequent chapters. The enrerohepatic circulation ofbile salts maintains bile salt dependent bile flow. Bile salts are excreted into bile and are largely absorbed in the terminal ileum and then efficiently removed from the portal circulation at the basolateral plasma membrane of the heparocyte. Each of these steps is dependent on the function of bile salt transport proteins.…

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Condition: Sehr gut. Zustand: Sehr gut | Sprache: Englisch | Produktart: Bücher | In recent years there has been an increasing need for transplantation, but the number of donor livers available has increased only slightly, despite intensive public relations activities. New concepts in the field of transplantation, for instance the transplantation of living donor organs or the splitting of organs, are urgently required, to safeguard the treatment of patients with severe liver disease. The development and clinical application of cell therapy for patients with liver disease could soon present a significant enhancement of the therapeutic options. The aim of such cell therapy is to repair or improve the biological function of the chronically and acutely damaged liver. Even though systematic trials are not available, individual case reports and small series already show promising clinical results. Present concepts of cell therapy for liver diseases based on the use of primary hepatocytes have recently been considerably extended through new data on the biology of stem cells. The adult haematopoetic stem cell as a pool for hepatocyte grafts - what would be the perspectives for the clinical application.…

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Condition: Used. pp. 380.

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Condition: Sehr gut. Zustand: Sehr gut | Seiten: 340 | Sprache: Englisch | Produktart: Bücher | Keine Beschreibung verfügbar.

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Condition: New. In recent years there has been an increase in the need for transplantation, but the number of donor livers available has increased only slightly, despite intensive public relations activities. The development and application of cell therapy for patients with liver disease could present a significant enhancement of the therapeutic options. Editor(s): Gupta, S.; Jansen, P.L.M. (University Hospital, Groningen, Netherlands); Klempnauer, J. (Gastroenterologie/Hepatologie, Medizinische Hochschule Hannover, Germany); Manns, M. P. Series: Falk Symposium. Num Pages: 190 pages, biography. BIC Classification: MJJ; MNG. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly. Dimension: 234 x 156 x 12. Weight in Grams: 990. . 2002. Hardback. . . . .…

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Gebunden. Condition: New. In recent years there has been an increasing need for transplantation, but the number of donor livers available has increased only slightly, despite intensive public relations activities. New concepts in the field of transplantation, for instance the tra.

Condition: New. In recent years there has been an increase in the need for transplantation, but the number of donor livers available has increased only slightly, despite intensive public relations activities. The development and application of cell therapy for patients with liver disease could present a significant enhancement of the therapeutic options. Editor(s): Gupta, S.; Jansen, P.L.M. (University Hospital, Groningen, Netherlands); Klempnauer, J. (Gastroenterologie/Hepatologie, Medizinische Hochschule Hannover, Germany); Manns, M. P. Series: Falk Symposium. Num Pages: 190 pages, biography. BIC Classification: MJJ; MNG. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly. Dimension: 234 x 156 x 12. Weight in Grams: 990. . 2002. Hardback. . . . . Books ship from the US and Ireland.…

Buch. Condition: Neu. Neuware - In recent years there has been an increasing need for transplantation, but the number of donor livers available has increased only slightly, despite intensive public relations activities. New concepts in the field of transplantation, for instance the transplantation of living donor organs or the splitting of organs, are urgently required, to safeguard the treatment of patients with severe liver disease. The development and clinical application of cell therapy for patients with liver disease could soon present a significant enhancement of the therapeutic options. The aim of such cell therapy is to repair or improve the biological function of the chronically and acutely damaged liver. Even though systematic trials are not available, individual case reports and small series already show promising clinical results. Present concepts of cell therapy for liver diseases based on the use of primary hepatocytes have recently been considerably extended through new data on the biology of stem cells. The adult haematopoetic stem cell as a pool for hepatocyte grafts - what would be the perspectives for the clinical application.…

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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -membrane contamination and thus could then be used to study transport function when pre pared as membrane vesicles. These approaches defined a number of transport functions in the plasma membranes of hepatocyres and ultimately led to the recognition that bile salts and 3 25 other solutes were transported into bile largely by ATP dependent transport mechanisms.2 - The advent ofmolecular cloning techniques and cellular expression systems rapidly acceler ated progress in this field and led to the molecular characterization ofmost ofthe major mem brane transport proteins that determine both the hepatic uptake of organic solutes as well as bile salt dependent and bile salt independent canalicular excretion. Overview of the Molecular Mechanisms of Bile Formation The major transporters that determine bile formation are illustrated in Figure 1 and are discussed in greater detail in the subsequent chapters. The enrerohepatic circulation ofbile salts maintains bile salt dependent bile flow. Bile salts are excreted into bile and are largely absorbed in the terminal ileum and then efficiently removed from the portal circulation at the basolateral plasma membrane of the heparocyte. Each of these steps is dependent on the function of bile salt transport proteins. 384 pp. Englisch.…

Condition: New. Print on Demand pp. xiii + 366.

Condition: New. PRINT ON DEMAND pp. xiii + 366.