Roger Bertolotti (30 results)

Condition: New. pp. 558.

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Condition: Brand New. New. US edition. Expediting shipping for all USA and Europe orders excluding PO Box. Excellent Customer Service.

Condition: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.

Condition: Used. pp. xli + 446.

Condition: Used. pp. xli + 446 Illus.

Condition: Used. pp. xli + 446.

Hardcover. Condition: Brand New. 490 pages. 9.75x6.75x1.25 inches. In Stock.

Condition: New. Brand new book, sourced directly from publisher. Dispatch time is 6-7 days from our warehouse. Book will be sent in robust, secure packaging to ensure it reaches you securely.

HRD. Condition: New. New Book. Shipped from UK. Established seller since 2000.

Condition: New.

Hardcover. Condition: new. Hardcover. The first unequivocal success for Gene Therapy was reported in April 2000 for X-SCID patients. Pioneering stem cell/gene therapy clinical trials are the focus of this book. Therapy successes such as the X-SCID trial and improved ADA-SCID ones are presented together with pioneering angio/vasculogenic clinical trials mediated either by transient gene therapy or emerging autologous stem cell transplantation. Highlights also include 1) promises of the breakthrough combination of stem cell- and transient gene-therapy, 2) gene therapy trials for neurodegenerative disease on non-human primates where long-term gene therapy might involve brain stem cells, and 3) the first clinical trial with non-invasive monitoring of therapeutic gene expression as a prospective conclusion. The first unequivocal success for Gene Therapy was reported in April 2000 for X-SCID patients Shipping may be from multiple locations in the US or from the UK, depending on stock availability.…

HRD. Condition: New. New Book. Shipped from UK. Established seller since 2000.

Gebunden. Condition: New. Adult or postnatal stem cells offer life-long cell replacement in tissues and organs. This book discusses pathologies in terms of stem cell repopulation dynamics, with appropriate niches (long-term engraftment) and tissues (cell turnover).Inhaltsver.

Condition: New.

Condition: As New. Unread book in perfect condition.

Condition: As New. Unread book in perfect condition.

Hardcover. Condition: Like New. LIKE NEW. SHIPS FROM MULTIPLE LOCATIONS. book.

Condition: New. pp. vi + 356.

Condition: New. Roger Bertolotti, CNRS, Molecular Genetics, Department of Hepato-Gastroenterology, Faculty of Medicine, University of Nice-Sophia Antipolis, France. Keiyo Ozawa, Division of Hematology, Department of Medicine, and Division of Cell Transplantation and Transf.

Buch. Condition: Neu. Neuware - Stem cells provide for life-long cell replacement in tissues and organs, and have inherent homing abilities that are critical in therapeutic applications. Stem cells are also the driving force of cancer where genetic/epigenetic alterations culminate in tumorigenesis either in tissue stem cells or in some of their derivatives. As a rare subset of the tumor, cancer stem cells are the only drive of tumor initiation/propagation. Autologous and cancer stem cells are thus the key targets of 1) long-term and transient-regenerative/epigenetic gene therapy and 2) of recurrence-free anticancer therapy, respectively. While cancer stem cell gene therapy still needs time to accomplish, autologous stem cells have been instrumental in the first unequivocal successes for gene therapy whereby ex vivo retrovirally corrected hematopoietic stem cells have been returned to the patients.This timely book presents 1) the aforementioned stem cell gene therapy achievements that rely on random-integration of therapeutic transgenes into host chromosomes and 2) emerging experimental approaches aimed at eliminating random-integration oncogenic hazards through site-specific integration or gene targeting. Breakthrough endonuclease-boosted gene targeting for gene correction (inherited diseases) or targeted integration of therapeutic transgenes (other disorders) culminating in an efficiency compatible with clinical trials is one of the highlights of the book. Highlights also include the pioneering transplantation of adult pluripotent stem cells as a substitute for tissue-specific stem cells, thereby pinpointing the invaluable potential for stem cell gene therapy applications of autologous cells able to contribute to all three germ layers. Stem cell gene therapy is thus discussed in terms of 1) magnifying stem cell therapeutic homing through transient regenerative gene therapy and 2) of tackling most pathologies (including mitochondrial DNA diseases and ageing disorders) through stem cell repopulation dynamics into appropriate niches (long-term engraftment) and tissues (cell turn-over). Regarding cancer stem cell gene therapy, focus is on both the increasing number of identified tissue-specific cancer stem cells as the ultimate therapeutic targets and on the development of armed stem cells as tumor-homing vectors for targeted anticancer therapy.…

Hardcover. Condition: Brand New. illustrated edition. 330 pages. 9.50x6.25x0.75 inches. In Stock.

Condition: New. pp. vi + 356.

Buch. Condition: Neu. Neuware - The first unequivocal success for Gene Therapy was reported in April 2000 for X-SCID patients. Pioneering stem cell/gene therapy clinical trials are the focus of this book. Therapy successes such as the X-SCID trial and improved ADA-SCID ones are presented together with pioneering angio/vasculogenic clinical trials mediated either by transient gene therapy or emerging autologous stem cell transplantation. Highlights also include 1) promises of the breakthrough combination of stem cell- and transient gene-therapy, 2) gene therapy trials for neurodegenerative disease on non-human primates where long-term gene therapy might involve brain stem cells, and 3) the first clinical trial with non-invasive monitoring of therapeutic gene expression as a prospective conclusion. This volume will be of value and interest to researchers in this exciting field.…

Hardcover. Condition: new. Hardcover. The first unequivocal success for Gene Therapy was reported in April 2000 for X-SCID patients. Pioneering stem cell/gene therapy clinical trials are the focus of this book. Therapy successes such as the X-SCID trial and improved ADA-SCID ones are presented together with pioneering angio/vasculogenic clinical trials mediated either by transient gene therapy or emerging autologous stem cell transplantation. Highlights also include 1) promises of the breakthrough combination of stem cell- and transient gene-therapy, 2) gene therapy trials for neurodegenerative disease on non-human primates where long-term gene therapy might involve brain stem cells, and 3) the first clinical trial with non-invasive monitoring of therapeutic gene expression as a prospective conclusion. The first unequivocal success for Gene Therapy was reported in April 2000 for X-SCID patients Shipping may be from our Sydney, NSW warehouse or from our UK or US warehouse, depending on stock availability.…

hardcover. Condition: fine. first edition. Très fort in-4° relié demi-chagrin chamois de l époque - - Aphasie (Contribution à l'étude des localisations de l'.), par LA SALLE ARCHAMBAULT -- . de Broca (Restauration du langage dans l'.), par DEJERINE et ANDRÉ THOMAS -- Arthropathie (Troubles de l'écriture par . de l'épaule chez un tabétique), par GOMMÈS -- Atrophie musculaire chez un nègre, par AUSTREGESILO -- Chondrohypoplasie (Achondroplasie et . Contribution clinique), par RAVENNA -- Coagulation massive du liquide céphalo-rachidien et xanlochromie, par MARINESCO et RADOVICI -- Habsbourg (L'amour de la mort chez les .), par LAIGNEL LATASTINE -- Hémispasmes sycinétiques de la face liés au clignement des paupières dans les paralysies faciales, par PITRES (A.) et ABADIE (J.) -- Hémiatrophie, hémiparésie et hémi-hypoesthésie linguale gauche par nécrobiose ou hémorragie bulbaire, par ROGER (H.) et RAUZIER -- Hydrocéphalie interne (Réacutisation de l'. congénitale avec symptômes bulbaires), par CIUFFINI -- Hypertrophie crânienne simple familiale, par KLIPPEL et FELSTEIN -- Hypophysaire (Infantilisme .), par SOUQUES et CHAUVET -- . (L'achondroplasie répond-elle à une insuffisance . partielle ?), par BAUMEL et MARGAROT -- Hypophyse, rôle dans le diabète insipide et l'infantilisme, par LEREBOULLET, FAURE-BEAULIEU et VAUCHER -- Idéaliste passionné (Psychose à base d'interprétation passionnée. Un . de la justice et de la bonté), par DIDE et Mlle LEVÊQUE -- Idiotie et manie, par BENON -- Infantilisme et diabète insipide, Rôle de l'hypophyse, par LEREBOULLET, FAURE-BEAULIEU et VAUCHER - . hypophysaire, par SOUQUES et CHAUVET -- Insuffisance hypophysaire (L'achondroplasie repond-elle à une partielle ?), par BAUMEL et MARGAROT - Interprétation passionnée (Psychose à base d'. Un idéaliste passionné de la justice et de la bonté), par DIDE et Mlle LEVÊQUE -- Localisation de l'aphasie, par LA SALLE ARCHAMBAULT - Long extenseur propre du pouce, paralysie isolée, par CLUZET et NOVÉ-JOSSERAND -- Manie et idiotie, par BENON -- Manie chronique, par BENON et DENES -- Mégalo-dactylie unilatérale des orteils, par CHARPENTIER -- Méningite cervicale hypertrophique, par BABINSKI, JUMENTIÉ et JARKOWSKI - Méningo-encéphalite chronique, par SNESSAREFF -- Moelle (Modifications dans la . au cours des tumeurs siégeant dans la fosse postérieure du crâne), par RAIMISTE et NEIDING -- Moelle (tumeurs). traitement chirurgical, par ROTSTADT -- Momie égyptienne (Vertèbre lombaire surnu méraire complète chez une . de la XIe dynastie), par BERTOLOTTI - Myoclonies essentielles, par MONIZ -- Nerveuses (Formes . d'une nouvelle trypanosomiase), par CHAGAS -- Nerveux (Système) (Contribution à l'étude du . dans la paralysie agitante), par HASKOVEC et BASTA - Névrome d'amputation, un cas, par DUSTIN et LIPPENS -- dème congénital familial des extrémités inférieures, par BOKS -- Omoptates ailées physiologiques, par HNATEK -- Orteils (Un cas de mégalodactylie unilatérale des .), par CHARPENTIER -- Oxycéphalie et syndrome oxycéphalique, par CHARON et COURBON -- Paget (Etude de la base du crâne dans la maladie de .), par LÉRI -- Paralysie agitante (Contribution à l'étude du système nerveux dans la .), par HASKOVEC et BASTA -- . isolée du long extenseur propre du pouce, par CLUZET et NOVÉ-JOSSERAND -- . puerpérale du nerf sciatique poplité externe, du côté gauche, par NOICA et ZAHARESCA - Pied (Une variété de déformation du . chez une tabetique), par MARIE et BOUTTIER -- Processus de réparation dans le cerveau. Cas de méningo-encéphalite chronique avec at aques épileptiques, par SNESSAREFF -- Restauration du langage dans l'aphasie de Broca, par DEJERINE et ANDRÉ-THOMAS -- Sciatique (Paralysie puerpérale du nerf . poplité externe du coté gauche), par NOICA et ZAHARESCU -- Sclérodermie et syndrome de Basedow, par MARINESCO et GOLDSTEIN -- . (Etude radiologique d'un cas de . Analogies avec le syndrome de Profichet), par BERTOLOTTI -- Sein hystérique et suggestion, par CHARON et COURBON.…

Condition: New. Print on Demand pp. 558 This item is printed on demand.

Condition: New. PRINT ON DEMAND pp. 558.

Condition: New. pp. vi + 356 Illus. This item is printed on demand.