Willis Monte S (96 results)

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Condition: New. 1st edition NO-PA16APR2015-KAP.

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Hardcover. Condition: like new. XV, 543 p., hardcover, 250x167x35 mm, 2012, like new. Buch.

Hardback. Condition: As new. xiv + 335 pp. Molecular and Translational Medicine. book.

Paperback. Condition: Brand New. 313 pages. 9.21x6.14x0.67 inches. In Stock.

Condition: New. Salvatore V. Pizzo, Roger L. Lundblad, Monte S. WillisMost clinical laboratory tests utilize interstitial and extravascular such as blood, urine, cerebral spinal fluid (CSF), and saliva. For example, CSF is monitored in the context of canc.

Taschenbuch. Condition: Neu. Neuware - Most clinical laboratory tests utilize interstitial and extravascular such as blood, urine, cerebral spinal fluid (CSF), and saliva. For example, CSF is monitored in the context of cancer for both diagnostic and therapeutic reasons. And yet, our understanding of the makeup of interstitial fluids, their relationships to disease, as well as their commercial importance in therapeutics and diagnostics remains rudimentary. Although sometimes perceived as static, interstitial and extravascular fluids are surprisingly dynamic. More than half of serum albumin is in the extravascular space. These fluids move rapidly between the intravascular and extravascular spaces - one entire plasma volume is exchanged very nine hours. In the first half of the book, the authors cover fundamental concepts of interstitial fluids, including their composition and function. They then further review the mechanisms by which interstitial fluids are regulated, characterizing the importance of hyaluronan - a major constituent of interstitial spaces and an a component of synovial fluid; and, outlining the regulation of proteolysis in the interstitial space. In the second half of the book, the authors focus on the coagulation system. This system has been studied extensively in the context of vascular spaces. But many of its components exist in the interstitial spaces. Chapters are devoted to the fibrinolytic system, kallikrein, matrix metalloproteinases, coagulation factors, and protease inhibitors - all are interstitial. By covering a unique array of topics with broad application to biomedical scientists, this book expands our understanding of the importance of interstitial spaces and the fluids that move through and reside in this extravascular environment.…

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Condition: New. Translational Cardiology: Molecular Basis of Cardiac Metabolism, Cardiac Remodeling, Translational Therapies and Imaging Techniques provides an up-to-date introduction to the role circadian rhythms, cardiac plasticity, and mechanotransduction play in the heart, while at the same time introducing new developments in cellular, viral, and non-biologic therapies that are in the process of being developed. Importantly, the focus of this book is on topics that, due to their novelty, are largely not covered in the other major textbooks. A special emphasis is placed on the molecular basis of cardiac metabolism, new concepts in cardiac remodeling, and translational therapies and imaging techniques currently under development for clinical use. The chapters are written by experts from diverse clinical and biomedical research backgrounds. Translational Cardiology: Molecular Basis of Cardiac Metabolism, Cardiac Remodeling, Translational Therapies and Imaging Techniques simplifies the complexity of the molecular basis of disease by focusing on patient-oriented disease mechanisms and therapies and is of great value to a broad audience including physicians (e.g. cardiologists, cardiovascular surgeons, pathologists) as well as translational biomedical researchers in a wide range of disciplines.…

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Condition: New. . 2014. 2012th Edition. Paperback. . . . .

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Condition: Hervorragend. Zustand: Hervorragend | Seiten: 492 | Sprache: Englisch | Produktart: Bücher | Introduction.- The Role of Chemokines in Fibrotic dermal remodeling and wound healing.- Fibrosis and immune dysregulation in systemic sclerosis.- Macrophage Plasticity in Skin Fibrosis.- Fibrotic Signaling in the Lung.- Pulmonary Matrikines: Origin, Function and Contribution to Fibrotic and Non-Fibrotic Lung Disease.- The Role of Mast Cells in the Pathophysiology of Pulmonary Fibrosis.- PERICYTES AND T CELLS IN LUNG INJURY AND FIBROPROLIFERATION.- Emerging Therapeutic Targets and Therapies in Idiopathic Pulmonary Fibrosis.- Dynamic reciprocity- the role of the extracellular matrix microenvironment in amplifying and sustaining pathological lung fibrosis.- Fibrotic Signaling in Cardiomyopathies.- WNT SIGNALING AND CARDIAC FIBROSIS.- Matrix metalloproteinase-9-dependent mechanisms of reduced contractility and increased stiffness in the aging heart.- Using peptidomics to identify extracellular matrix-derived peptides as novel therapeutics for cardiac disease.- Vascular Fibrosis and Disease.- Liver Fibrosis: Current Approaches and Future Directions for Diagnosis and Treatment.- Tipping the balance from angiogenesis to fibrosis in chronic kidney disease.- Fibrotic Remodeling in Exudative (Wet) Macular Degeneration.…

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