Inflammasomes (85 results)

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Paperback. Condition: new. Paperback. The term inflammasome was coined over a decade ago to describe the molecular platform activated by pathogens or stressor molecules where inflammatory caspases are triggered and cleavage of IL-1ss takes place. Inflammasome regulation is critical for the maintenance of homeostasis: an imbalance in this fine-tuning is responsible for the establishment of infectious, autoimmune, metabolic and neurodegenerative diseases. This book examines the activation and function of inflammasomes during fungal infections; inflammasome involvement in carcinogenesis; and the role of inflammasomes in protozoan infections. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.…

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Condition: New. Editor(s): Mason, Angie. Num Pages: 72 pages, illustrations. BIC Classification: MJCJ; MJCM; PSB; PSF. Category: (P) Professional & Vocational. Dimension: 156 x 246 x 10. Weight in Grams: 162. . 2016. UK ed. Paperback. . . . .

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Condition: New. Editor(s): Mason, Angie. Num Pages: 72 pages, illustrations. BIC Classification: MJCJ; MJCM; PSB; PSF. Category: (P) Professional & Vocational. Dimension: 156 x 246 x 10. Weight in Grams: 162. . 2016. UK ed. Paperback. . . . . Books ship from the US and Ireland.

Paperback. Condition: new. Paperback. The term inflammasome was coined over a decade ago to describe the molecular platform activated by pathogens or stressor molecules where inflammatory caspases are triggered and cleavage of IL-1ss takes place. Inflammasome regulation is critical for the maintenance of homeostasis: an imbalance in this fine-tuning is responsible for the establishment of infectious, autoimmune, metabolic and neurodegenerative diseases. This book examines the activation and function of inflammasomes during fungal infections; inflammasome involvement in carcinogenesis; and the role of inflammasomes in protozoan infections. Shipping may be from our Sydney, NSW warehouse or from our UK or US warehouse, depending on stock availability.…

Condition: New. KlappentextrnrnThe term inflammasome was coined over a decade ago to describe the molecular platform activated by pathogens or stressor molecules where inflammatory caspases are triggered and cleavage of IL-1&#946 takes place. Inflammasome regu.

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Buch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - The inflammasome is a protein complex composed of an intracellular sensor-typically a Nod-like receptor (NLR), the precursor procaspase-1, and the adaptor ASC. Inflammasome activation leads to the maturation of caspase-1 and the processing of its substrates, IL-1beta and IL-18. The inflammasome has been implicated numerous diseases, and blockade of inflammasome-derived IL-1beta has beneficial effects on several of these diseases. Different books have been edited about the biology of inflammasomes and about methods to study, however, the implication of this complex in the different diseases and pathological conditions show the need of a book about the clinical implications and therapeutic options. This project will show the context where inflammasomes are being studied and the molecular implications in the medical and clinical contexts. Other important topic of the inflammasomes will be the development of pharmacological inhibitors in order to improve new clinical applications. In this sense, we can find new drugs with inhibitory effects or old drugs with an inhibitory potential effect. There is a need for re-establishing the real benefits of the inflammasome inhibitions in pathological situations and the management of the differents diseases where inflammasomes are implicated.…

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Taschenbuch. Condition: Neu. Inflammasomes: Clinical and Therapeutic Implications | Mario D. Cordero (u. a.) | Taschenbuch | Experientia Supplementum | viii | Englisch | 2019 | Springer | EAN 9783030077587 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.…

Taschenbuch. Condition: Neu. The Inflammasomes | Isabelle Couillin (u. a.) | Taschenbuch | Progress in Inflammation Research | xiv | Englisch | 2013 | Springer | EAN 9783034803434 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu. …

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Taschenbuch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - The inflammasome is a protein complex composed of an intracellular sensor-typically a Nod-like receptor (NLR), the precursor procaspase-1, and the adaptor ASC. Inflammasome activation leads to the maturation of caspase-1 and the processing of its substrates, IL-1beta and IL-18. The inflammasome has been implicated numerous diseases, and blockade of inflammasome-derived IL-1beta has beneficial effects on several of these diseases. Different books have been edited about the biology of inflammasomes and about methods to study, however, the implication of this complex in the different diseases and pathological conditions show the need of a book about the clinical implications and therapeutic options. This project will show the context where inflammasomes are being studied and the molecular implications in the medical and clinical contexts. Other important topic of the inflammasomes will be the development of pharmacological inhibitors in order to improve new clinical applications. In this sense, we can find new drugs with inhibitory effects or old drugs with an inhibitory potential effect. There is a need for re-establishing the real benefits of the inflammasome inhibitions in pathological situations and the management of the differents diseases where inflammasomes are implicated.…

Taschenbuch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - The inflammasome was first described in 2002 as a molecular complex activating proinflammatory caspases and therefore regulating the maturation and biological activities of cytokines such as IL-1 and IL-18. This finding was substantiated by the identification of several mutations in the cias1 gene, encoding the human NLRP3 protein, responsible for several autoinflammatory disorders such as the Muckle Wells syndrome. Since, the interest for this complex has constantly increased and several inflammasome complexes with different specificities have been described. These inflammasomes sense a wide variety of pathogens and danger signals and are key players in the inflammatory response. With the contributions of leading international experts in the field, this book provides an extensive overview of the current knowledge of inflammasome biology and their role in health and disease.…