Nucleic Acids Innate Immunity (32 results)

Hardback. Condition: New. Edited by Holger Heine, this collection of ten contributed chapters compares innate immunity in organisms across the evolutionary tree. It begins with plants, with a chapter on how resistance genes evolved, then turns to cnidarians. Two chapters on Drosophila melanogaster follow, one on humoral immune responses and one on cellular ones. Other chapters cover immune reactions in the urochordates, the closest invertebrate relatives of the vertebrates, and the innate immune system of the zebrafish. The later chapters move to mammals and humans, dealing with the main receptor systems, antimicrobial peptides and defense mechanisms. A chapter on the complement system in innate immunity closes the volume.…

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Hardcover/Pappeinband. Condition: Gut. XIV, 241 p. : ill. ; 24 cm. Guter Zustand. Bibliotheksexemplar mit Stempeln und Signatur auf Einband. Sonst Seiten sauber. / Good. Ex-library with usual markings. Clean pages. Sprache: Englisch Gewicht in Gramm: 530.

Paperback. Condition: Brand New. reprint edition. 286 pages. 9.00x6.00x0.75 inches. In Stock.

Condition: Hervorragend. Zustand: Hervorragend | Seiten: 302 | Sprache: Englisch | Produktart: Bücher | Until recently, innate immunity was regarded as a relatively nonspecific system designed to engulf and destroy pathogens. However, new studies show that the innate immune system is highly developed in its ability to discriminate between self and foreign entities. Understanding this mechanism can lead to therapeutic strategies based on manipulation of this previously unexploited branch of the immune system.Drawing on the research of leading experts, Nucleic Acids in Innate Immunity provides insight in this new area of immunology. The book begins by explaining the roles of nucleic acids in immunity, describing the mechanism of discrimination based on pattern-recognition receptors (PRRs), including Toll-like receptors (TLRs), Nod-like receptors (NLR), and RIG-I-like receptors (RLR). Chapters discuss how these PRRs recognize and respond to pathogen-associated molecular patterns (PAMPs) by activating specific signaling pathways.The second section focuses on the therapeutic applications of immunomodulatory DNA by manipulating released pathogenic nucleic acids as immune system stimulants. The book introduces novel therapeutics developed to prevent or treat infectious diseases, allergic disorders, and cancer, as well as clearing unnecessary or abnormal host molecules.The final section addresses how the immune system discriminates self and non-self RNA. Recent findings that host (self) nucleic acids are not inert in the immune system beg the question of exactly what elements within DNA or RNA are recognized by the innate immune system. Contributions review recent advances to understand innate immune recognition of nucleic acids and describe the resulting immune modulation.Providing a comprehensive review of nucleic acid recognition and regulation by the innate immune system, this seminal work reveals new directions for future research in immune modulation.…

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Hardcover. Condition: Brand New. 1st edition. 286 pages. 9.25x6.50x0.75 inches. In Stock.

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Condition: gut. 2008. Innate immunity of plants, animals, and humans (=Nucleic acids and molecular biology ; Vol. 21). In deutscher Sprache. pages.

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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Ken J. Ishii, Shizuo AkiraUntil recently, innate immunity was regarded as a relatively nonspecific system designed to engulf and destroy pathogens. However, new studies show that the innate immune system is highly developed in its ability to disc.…

Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Providing insight into new areas of immunology, this book explains the roles of nucleic acids in immunity, describing the mechanism of discrimination based on pattern-recognition receptors (PRRs). Chapters discuss how these PRRs recognize and respond to pathogen-associated molecular patterns (PAMPs) by activating specific signaling pathways. The book focuses on the therapeutic applications of immunomodulatory DNA to prevent or treat infectious diseases, allergic disorders, and cancer and addresses how the immune system discriminates self and non-self RNA. Contributions review recent advances to understand exactly what elements within DNA or RNA activate the innate immune recognition of nucleic acids and describe the resulting immune modulation.…