Abbot Vikrant (48 results)

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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Some new amino substituted quinazoline compounds were synthesized and evaluated for their anticancer activity at National Cancer Institute (NCI), U.S.A. Among the synthesized nine compounds, two were selected for single high dose screening (10-5 M) in full 60 cell panel. Among the selected compounds, 2-benzamido-N-(benzo[d]thiazol-2-yl)benzamide 4 exhibited significant anticancer activity against non-small cell lung cancer NCI-H23, colon cancer HCT-15, CNS cancer SF-539, melanoma SK-MEL-5, ovarian cancer OVCAR-8, renal cancer ACHN, prostate cancer PC-3 and breast cancer MCF7 with inhibition rate of 97.82%, 99.67%, 99.21%, 90.75%, 99.21%, 99.31%, 97.23% and 93.29% respectively. This compound was selected for testing under five dose level screening against 60 cancer cell lines. The results of five dose assay revealed significant anticancer activity of this compound against almost all cancer cell lines. 80 pp. Englisch.…

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Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Some new amino substituted quinazoline compounds were synthesized and evaluated for their anticancer activity at National Cancer Institute (NCI), U.S.A. Among the synthesized nine compounds, two were selected for single high dose screening (10-5 M) in full 60 cell panel. Among the selected compounds, 2-benzamido-N-(benzo[d]thiazol-2-yl)benzamide 4 exhibited significant anticancer activity against non-small cell lung cancer NCI-H23, colon cancer HCT-15, CNS cancer SF-539, melanoma SK-MEL-5, ovarian cancer OVCAR-8, renal cancer ACHN, prostate cancer PC-3 and breast cancer MCF7 with inhibition rate of 97.82%, 99.67%, 99.21%, 90.75%, 99.21%, 99.31%, 97.23% and 93.29% respectively. This compound was selected for testing under five dose level screening against 60 cancer cell lines. The results of five dose assay revealed significant anticancer activity of this compound against almost all cancer cell lines.…

Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Abbot VikrantMr. Vikrant Abbot is working as Assistant Professor at ISF College of Pharmacy, Moga, Punjab, India.Some new amino substituted quinazoline compounds were synthesized and evaluated for their anticancer activity at Nat.…

Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Thioredoxin (Trx) (12 kDa M.W.) is a ubiquitous antioxidant protein which controls the oxidative stress and redox signaling with thioredoxin reductase (TrxR) and NADPH. Trx acts as an electron donor for ribonucleotide reductase (RNR), methionine sulfoxide reductase (Msr), and Trx peroxidase (peroxiredoxin). Trx plays an important role in DNA synthesis, reduction of the disulfide bond, recycling of peroxiredoxin (Prx), and as an electron donor. Various in vivo and in vitro assays are used to check the activity of Trx. This work is focused on the study of in vivo and in vitro methods for Trx activity which have been used in the different model system. Different methods were studied to evaluate the activity of Trx in different samples. Insulin reduction assay is more commonly used in vitro method because insulin acts as effective substrate for activity of Trx. Fluorescence, DTNB (5, 5 -dithiobis (2-nitrobenzoic acid)) reduction, spectrophotometric or micro-method insulin reduction, and disulfide cross-linking interaction in vitro assays while Luciferase, cloning, and wort in vivo assays are used for the activity of the Trx system.…

Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Thioredoxin (Trx) (12 kDa M.W.) is a ubiquitous antioxidant protein which controls the oxidative stress and redox signaling with thioredoxin reductase (TrxR) and NADPH. Trx acts as an electron donor for ribonucleotide reductase (RNR), methionine sulfoxide r.…

Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Seeds of E. jambolana are known to possess anti-diabetic activity as well as other pharmacological activities. Various phytoconstituents are also reported to be present in the seeds. But there is no report on any correlation between anti-diabetic activity & the phytoconstituents present in it. Hence the present study is designed to isolate and characterize phytoconstituents from ethanolic and aqueous extracts of seeds of Eugenia jambolana. The anti-diabetic constituent has also been identified.…

Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Kaur AmarjitMs. Amarjit kaur has completed B.Pharm from Govt. Polytechnic College of Girls, Patiala and M.pharm from Department of Pharmaceutical Sciences and Drug research, Punjabi university, Patiala. She has worked in Swift group .…

Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Some new amino substituted quinazoline compounds were synthesized and evaluated for their anticancer activity at National Cancer Institute (NCI), U.S.A. Among the synthesized nine compounds, two were selected for single high dose screening (10-5 M) in full 60 cell panel. Among the selected compounds, 2-benzamido-N-(benzo[d]thiazol-2-yl)benzamide 4 exhibited significant anticancer activity against non-small cell lung cancer NCI-H23, colon cancer HCT-15, CNS cancer SF-539, melanoma SK-MEL-5, ovarian cancer OVCAR-8, renal cancer ACHN, prostate cancer PC-3 and breast cancer MCF7 with inhibition rate of 97.82%, 99.67%, 99.21%, 90.75%, 99.21%, 99.31%, 97.23% and 93.29% respectively. This compound was selected for testing under five dose level screening against 60 cancer cell lines. The results of five dose assay revealed significant anticancer activity of this compound against almost all cancer cell lines.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 80 pp. Englisch.…