Seller: butzle, Buttenwiesen, DE, Germany
Gebundene Ausgabe. Condition: Gut. B378-3 9783883790084 Sprache: Deutsch Gewicht in Gramm: 1982.
Seller: butzle, Buttenwiesen, DE, Germany
Gebundene Ausgabe. Condition: Gut. B470-194 9783883790084 Sprache: Deutsch Gewicht in Gramm: 1982.
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Paperback or Softback. Condition: New. Novel Pharmacological Inhibitors for Bacterial Protein Toxins. Book.
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Hardcover. Condition: As New. 1. Auflage. like new.
Condition: New. KlappentextrnrnMany medically relevant bacteria cause severe human and animal diseases because they produce and release protein toxins that target mammalian cells. Because the toxin-induced cell damage is the reason for the clinical symptoms, th.
Seller: Sigrun Wuertele buchgenie_de, Altenburg, Germany
Condition: Sehr gut - gebraucht. Gebundene Ausgabe Sehr guter Zustand, ohne Namenseintrag, Original-Schutzumschlag Zustand: 2, Sehr gut - gebraucht, Gebundene Ausgabe Harenberg , 1977 , Die Musik. Menschen, Instrumente und Ereignisse in Bildern und Dokumenten, Holger Fliessbach, Horst Leuchtmann Barth, Christian, 3883790087, BU380564.
Seller: AHA-BUCH GmbH, Einbeck, Germany
Taschenbuch. Condition: Neu. Neuware - Many medically relevant bacteria cause severe human and animal diseases because they produce and release protein toxins that target mammalian cells. Because the toxin-induced cell damage is the reason for the clinical symptoms, the targeted pharmacological inhibition of the cytotoxic mode of action of bacterial toxins should prevent or cure the respective toxin-associated disease. Toxin inhibitors might be beneficial when the toxin acts in the absence of the producing bacteria (e.g., food poisoning), but also in combination with antibiotics in infectious diseases when the toxin-producing bacteria are present. The focus of this Special Issue of Toxins is on the development and characterization of novel inhibitors against bacterial toxins, e.g., toxin neutralizing antibodies, peptides or small compounds, as well as toxin pore blockers, which interfere with bacterial toxins and thereby protect cells from intoxication.
Published by kA, 1983
Seller: Antiquariat Wortschatz, Markt Hartmannsdorf, Austria
Hardcover. Condition: Gut. kA (illustrator). kA. Auflage. Anzahl Bände: 1 - Bd.Nr.: kA - Sprache: de - Einband: Hardcover - Gewicht: 301 - Illust.: kA - Zustand: Gut - leichte Lager- und Gebrauchsspuren.
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Language: English
Published by Springer International Publishing, 2018
ISBN 10: 3319865021 ISBN 13: 9783319865027
Seller: preigu, Osnabrück, Germany
Taschenbuch. Condition: Neu. Uptake and Trafficking of Protein Toxins | Holger Barth | Taschenbuch | vii | Englisch | 2018 | Springer International Publishing | EAN 9783319865027 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.
Condition: New. pp. 256.
Language: English
Published by Springer International Publishing, Springer International Publishing, 2018
ISBN 10: 3319865021 ISBN 13: 9783319865027
Seller: AHA-BUCH GmbH, Einbeck, Germany
Taschenbuch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - This volume focuses on the transport of medically relevant bacterial protein toxins into mammalian cells, and on novel pharmacological strategies to inhibit toxin uptake. The first chapters review our current understanding of the cell-surface receptors and cellular transport processes of Clostridium botulinum neurotoxins, Clostridium botulinum C3 toxin, Clostridium difficile toxins, binary clostridial enterotoxins, anthrax toxins and diphtheria toxin. In brief, specific binding/transport (B) subunits deliver the enzyme (A) subunits into the cytosol, where the latter modify their substrates, producing cytotoxic effects and the characteristic toxin-associated diseases. Key mechanisms for the transport of the A subunits from endosomes into the cytosol and the role of trans-membrane pores formed by the B subunits and host cell chaperones for this process are reviewed. The book's closing chapters focus on compounds which inhibit the transport of the A subunits from endosomes into the cytosol and therefore might lead to novel therapeutic strategies for toxin-associated diseases. These substances include pharmacological inhibitors of the host cell chaperones involved, as well as multivalent and heterocyclic molecules that specifically block the toxins' translocation channels. This volume offers an up-to-date resource for scientists.
Buch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - This volume focuses on the transport of medically relevant bacterial protein toxins into mammalian cells, and on novel pharmacological strategies to inhibit toxin uptake. The first chapters review our current understanding of the cell-surface receptors and cellular transport processes of Clostridium botulinum neurotoxins, Clostridium botulinum C3 toxin, Clostridium difficile toxins, binary clostridial enterotoxins, anthrax toxins and diphtheria toxin. In brief, specific binding/transport (B) subunits deliver the enzyme (A) subunits into the cytosol, where the latter modify their substrates, producing cytotoxic effects and the characteristic toxin-associated diseases. Key mechanisms for the transport of the A subunits from endosomes into the cytosol and the role of trans-membrane pores formed by the B subunits and host cell chaperones for this process are reviewed. The book's closing chapters focus on compounds which inhibit the transport of the A subunits from endosomes into the cytosol and therefore might lead to novel therapeutic strategies for toxin-associated diseases. These substances include pharmacological inhibitors of the host cell chaperones involved, as well as multivalent and heterocyclic molecules that specifically block the toxins' translocation channels. This volume offers an up-to-date resource for scientists.
Seller: Revaluation Books, Exeter, United Kingdom
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Add to basketHardcover. Condition: Brand New. 1st edition. 256 pages. 9.25x6.25x0.75 inches. In Stock.
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Add to basketPaperback. Condition: Brand New. reprint edition. 264 pages. 9.25x6.10x0.60 inches. In Stock.
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Add to basketPaperback. Condition: New. NEW. SHIPS FROM MULTIPLE LOCATIONS. book.