Holowka Eric (26 results)

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Taschenbuch. Condition: Neu. Copolypeptide Vesicles: Size Control for Intracellular Drug Delivery | Self-Assembled Copolypeptide Morphologies for Biomedical Applications | Eric Holowka | Taschenbuch | Englisch | VDM Verlag Dr. Müller | EAN 9783639179965 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu.…

Taschenbuch. Condition: Neu. Drug Delivery | Materials Design and Clinical Perspective | Eric P. Holowka (u. a.) | Taschenbuch | xvii | Englisch | 2016 | Humana | EAN 9781493946044 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu. …

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Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Much focus has been given to the synthesis of polypeptidic based materials due to their unique structural features. These polypeptides commonly are amphiphilic in character that benefit from secondary structural features associated with one of the polymer blocks. These features, such as alpha- helix and beta-sheet conformations, allow for control over nanoscale ordering through self- assembly for use in biological sensors and therapeutic drug delivery. We report the preparation and characterization of charged amphiphilic block copolypeptide vesicle formers using transition metal mediated living ring-opening polymerization of N- carboxyanhydrides (NCAs). The vesicle membranes show fluidic properties suggested by dynamic physical behavior allowing for fine size adjustments using liposomal extrusion methods. This extrusion also allows for a facile mode of encapsulation of biomolecules for drug delivery. Modification of the charged residues has shown vesicle stability under osmotic and thermal stress, in pH buffers, and serum cell media, as well as the ability for lipid and cellular interactions.…

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Kartoniert / Broschiert. Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Holowka EricEric Holowka earned a bachelor s degree in Chemistry from Carnegie Mellon University in 2001, while researching at the Center for Macromolecular Engineering. He then pursued research at the California Nanosystems Insti.…

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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Provides a comprehensive description of drug delivery systems from a materials perspective Includes a wide-ranging discussion of clinical applications of drug delivery systems Presents separate chapters on controlled release materials, thin.…

Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Provides a comprehensive description of drug delivery systems from a materials perspective Includes a wide-ranging discussion of clinical applications of drug delivery systems Presents separate chapters on controlled release materials, thin.…

Buch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Current pharmaceutical and clinical approaches to the treatment of disease suffer from the inherent limitations in the specialization of drugs introduced to physiological systems. The interface of clinical and material sciences has allowed for a broad spectrum of creative approaches with the potential to alleviate these shortcomings. However, the synergy of these disciplines also presents problems in which nascent technology lacks the necessary evaluation within its intended clinical environment. Given the growing potential for materials science to address a number of unanswered therapeutic needs, it remains even more pressing to validate emerging drug delivery technologies in actual clinical environments.Drug Delivery: Materials Designand Clinical Perspective addresses the core fundamentals of drug delivery using material science and engineering principles, and then applies this knowledge using prominent examples from both the scientific literature and clinical practice. Each chapter focuses on a specific drug delivery technology, such as controlled-release materials, thin-film materials, or smart materials. Within each chapter, an initial section on ¿Engineering Concepts¿ reviews the relevant fundamental principles that guide rational design. The following section on ¿Materials Design¿ discusses how the design process applies engineering concepts for use in physiological systems. A third section on ¿Implementation¿ discusses current approaches in the literature which have demonstrated effective drug delivery in controlled environments. Finally, each chapter contains several sections on ¿Clinical Applications¿ which describe the validity of materials approaches from a clinical perspective; these sections review the safety and efficacy of drug delivery systems for specific, compelling medical applications. The book thereby bridges materials science with clinical medicine, and provides the reader with a bench-to-bedside view of novel drug delivery systems. Provides a comprehensive description of drug delivery systems from a materials perspective Includes a wide-ranging discussion of clinical applications of drug delivery systems Presents separate chapters on controlled release materials, thin film materials, self-microemulsifying materials, smart materials, etc. Covers fundamental engineering principles, rational materials design, implementation testing, and clinical applications for each material typeSpringer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 376 pp. Englisch.…

Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Current pharmaceutical and clinical approaches to the treatment of disease suffer from the inherent limitations in the specialization of drugs introduced to physiological systems. The interface of clinical and material sciences has allowed for a broad spectrum of creative approaches with the potential to alleviate these shortcomings. However, the synergy of these disciplines also presents problems in which nascent technology lacks the necessary evaluation within its intended clinical environment. Given the growing potential for materials science to address a number of unanswered therapeutic needs, it remains even more pressing to validate emerging drug delivery technologies in actual clinical environments.Drug Delivery: Materials Designand Clinical Perspective addresses the core fundamentals of drug delivery using material science and engineering principles, and then applies this knowledge using prominent examples from both the scientific literature and clinical practice. Each chapter focuses on a specific drug delivery technology, such as controlled-release materials, thin-film materials, or smart materials. Within each chapter, an initial section on ¿Engineering Concepts¿ reviews the relevant fundamental principles that guide rational design. The following section on ¿Materials Design¿ discusses how the design process applies engineering concepts for use in physiological systems. A third section on ¿Implementation¿ discusses current approaches in the literature which have demonstrated effective drug delivery in controlled environments. Finally, each chapter contains several sections on ¿Clinical Applications¿ which describe the validity of materials approaches from a clinical perspective; these sections review the safety and efficacy of drug delivery systems for specific, compelling medical applications. The book thereby bridges materials science with clinical medicine, and provides the reader with a bench-to-bedside view of novel drug delivery systems. Provides a comprehensive description of drug delivery systems from a materials perspective Includes a wide-ranging discussion of clinical applications of drug delivery systems Presents separate chapters on controlled release materials, thin film materials, self-microemulsifying materials, smart materials, etc. Covers fundamental engineering principles, rational materials design, implementation testing, and clinical applications for each material typeSpringer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 376 pp. Englisch.…