Penicillin (12 results)

Condition: Fair. This book has hardback covers. Ex-library, With usual stamps and markings, In fair condition, suitable as a study copy. No publication date. Please note the Image in this listing is a stock photo and may not match the covers of the actual item,300grams, ISBN:

Broschiert. Condition: Sehr gut. Penicillin-Gesellschaft Dauelsberg (Hg.) - Antibakterielles Praktikum Broschiert - Penicillin-Gesellschaft Dauelsberg Göttingen - 1968 - 36 Seiten Aus dem Inhalt: Fisteln Furunkel Otitis media Prostatitis Panaritium Sepsis und mehr Zustand: Gebräunt, aber insgesamt sauber und in sehr gutem Zustand, ohne Eintragungen oder Markierungen! Size: 18 x 13 cm. Buch.

8vo. 47 S. OLn. mit Goldprägung. Einband leicht berieben und fleckig, sonst gut erhaltenes Exemplar. Aus dem Besitz des Medizinhistorikers Manfred Stürzbecher (1928 in Berlin - 2020 ebenda). Sprache: deutsch.

(26 x 18,5 cm). 2 Bll., SS. 109-224, XXXII S. Anzeigen. Mit zahlreichen Abbildungen. Original-Broschur. (The British Journal of Surgery). Exemplar aus der Bibliothek von Norman Heatley mit dessen handschriftlichem Namenszug auf dem Einband. - Der britische Biochemiker Heatley (1911-2004) war wesentlich an der industriellen Produktion von Penicillin beteiligt.

Condition: Sehr gut. Zustand: Sehr gut | Seiten: 324 | Sprache: Englisch | Produktart: Bücher | Keine Beschreibung verfügbar.

Condition: Fine. Number of books: 1 book.

SOFTCOVER. Condition: AS NEW. 1st Edition Thus. Mde to commemorate the 50th anniversary of the discovery of penicillin and published by Beecham Research Laboratories in 1979. 4to in black printed orange card covers, pages numbered 191 to 236 - a very nicely produced facsimile, using well matched paper of the exact size of the complete issue for June 1929 which contains Flemings famous paper. Housed in a cloth backed thin card slip-case with single leaf insert on thick glossy paper with a brief history and time-line for penicillin. Fleming made his own limited edition reprint of the offprint in 1944, but this is the first reprint of the whole issue. . [CONDITION: The journal and insert are AS NEW, the slipcase is a little shelf rubbed and faintly sunned. Overall an excellent copy of this facsimile which has become almost as hard to find as the original ] . . __NOTE. Depending on destination, this item may require an extra payment for shipping insurance. If so, orders made by card will be completed only after you have approved the extra cost. . We always ship in STRONG PROTECTIVE CARD PARCELS.

A culture vessel used for the production of penicillin, from the collection of the vessel's designer, Norman Heatley. It was used by Howard Florey's research team, who pioneered the drug's clinical use. It is offered with Heatley's collection of offprints by Florey, as well as the papers that announced their discovery: "Penicillin as a Chemotherapeutic Agent" (1940) and "Further Observations on Penicillin" (1941). Although penicillin was discovered in 1928 by Alexander Fleming, it "might well have become an obscure scientific curiosity but for the work of Chain and Florey" (PMM). It was not until 1938, when Florey (1898-1968) and his team at the University of Oxford began working on it, that its therapeutic potential was fully realized. However, a major challenge was producing enough of the drug to treat an adult patient. This problem was solved by Heatley (1911-2004), a "genius for improvisation and invention", who developed the back-extraction technique, enabling penicillin to be efficiently purified in bulk (ODNB). The next obstacle was producing sufficient culture vessels for the new technique during wartime. With metal in short supply and glass prohibitively expensive, the team repurposed domestic items such as baking trays and bedpans from the Radcliffe Infirmary. The bedpans proved particularly effective, inspiring Heatley to design his own version. Produced by James MacIntyre & Co. in Burslem, Staffordshire, in 1940, the vessels were glazed on the inside to be watertight, unglazed on the outside to prevent slippage, and stackable to save space during fermentation. "This unassuming object made it possible for the first clinical trials of penicillin to take place" (BBC/British Museum). In 1941, Florey and Heatley travelled to the US with the evidence from these trials to convince American pharmaceutical companies to undertake mass production of the drug. By 1943, penicillin was in use, "saving hundreds of thousands of lives during World War II" (Norman). Florey received the Nobel Prize in 1945, along with Fleming and Ernst Chain. Although Heatley was not awarded the prize (which limits recipients to three), he received an honorary doctorate of medicine from Oxford in 1990, the first time a non-physician received the award. The crucial role that each individual played in turning penicillin into a usable drug was famously summarized by Henry Harris, Florey's successor as head of pathology at Oxford: "Without Fleming, no Florey or Chain. Without Chain, no Florey. Without Florey, no Heatley. Without Heatley, no penicillin". In 1994, Heatley gifted the vessel and offprints to his neighbour, David Cranston, the author of Penicillin and the Legacy of Norman Heatley (2016). A signed copy is included with the collection, along with related ephemera such as an autograph letter from Heatley discussing the offprint collection and the order of service for Heatley's funeral. The offprints are a representative selection of Florey's wide research interests throughout his career. They include his paper on the antimicrobial enzyme lysozyme - the study of which sparked his interest in penicillin - and his post-penicillin work on antibiotics, particularly against tuberculosis. A copy of the Royal Society's Florey bibliography, annotated to show the contents of this collection, is available upon request. Similar examples of Heatley's culture vessel have appeared at auction twice in the last 20 years: Christie's 2004 and Willingham 2022. Garrison-Morton 1934; Norman 437; Printing and the Mind of Man 420b: all "Penicillin as a Chemotherapeutic Agent". "Penicillin culture vessell", A History of the World, BBC & British Museum. Together, 83 items, comprising ceramic culture vessel, 77 offprints, and 5 ephemeral pieces, housed in 2 custom red cloth boxes. Vessel soiled from use, spout joint sometime repaired with glue, small chip to rim: in very good condition. Tape repair to "Penicillin as a chemotherapeutic agent" affecting text, else offprints in fine or near-fine condition.

4to. 1 p. Gedruckter Briefkopf. Inhaltsreicher Brief an Dr. T. L. Story über Penicillin: [] As regards penicillin in colds. This is a tricky matter. It has no effect on the virus but then how many so called colds are due to virus. I think that many are simple bacterial infections and even then, if the virus is the primary infection most of the troubles after the first two days are due to the secondary bacterial infection. There can be no doubt that penicillin is effective on all these bacteria except Pfeiffer's bacillus and even some of these are sensitive. In the past we have been very quiet about the use of penicillin as a 'cold cure.' There have been so many flops in that direction and as regards the extract from Lapin issued by Bristol and Co., this is just what I was afraid would happen. If this system does not develop fast organisms it would be excellent, but it would be a disaster if it bred out resistant races []I suppose it would be necessary to give about 50,000 units of penicillin twice a day. This would be quite expensive. If you do anything like that I shall be very glad indeed to know the result. []" Beiliegend: 1 Durchschlag von Dr. Storys-Brief an Fleming. 1 1/4 p., 4to, 30. Oktober 1947.

8vo. 1 p. Gedr. Briefkopf The Wright-Fleming Institute of Microbiology". Here is your autograph | Alexander Fleming | 26/4/49". Darunter ein Portrait des Wissenschaftlers montiert.Fleming studierte ab 1902 Medizin an der St Mary's Hospital Medical School in Paddington. 1906 schloss er sein Studium ab, blieb aber weiterhin am Institut. Ab 1921 war er stellvertretender Leiter und ab 1946 Direktor des Instituts, das 1948 in Wright-Fleming-Institut umbenannt wurde. Von 1928 bis 1948 hatte er an der Londoner Universität den Lehrstuhl für Bakteriologie inne.

Quer-8vo. 1 p. Der saubere Namenszug AFleming" wurde einem Brief entnommen und auf ein größeres Albumblatt (quer-8vo.) geklebt.

No binding. Condition: fine. n.d. (c.1950's) Print Paper Size: 24cm x 19cm (Image Size: 24cm x 19cm). Frame: 32.1x25.8cm. Edges of frame somewhat rubbed. [aj1509-102738].