Complement Kidney Disease (23 results)
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Taschenbuch. Condition: Neu. Complement regulatory proteins and chronic kidney disease | Expression levels of complement regulatory proteins on peripheral blood cells of patients with chronic kidney disease | Alshaymaa Alhabibi Et Al | Taschenbuch | Englisch | 2021 | LAP LAMBERT Academic Publishing | EAN 9786200215543 | Verantwo…rtliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu.
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Condition: New. It is evident that a defective or deregulated complement system results in kidney diseases. An important role of complement effector and regulatory proteins in pathological settings of the kidney has been demonstrated. This book discusses Molecular biology, clinics and therapy. Editor(s): Zipfel, Peter F. Series:… Progress in Inflammation Research. Num Pages: 252 pages, biography. BIC Classification: MFG; MJCM; MJR; MMFM; PSF. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 16. Weight in Grams: 603. . 2005. 2006th Edition. hardcover. . . . .
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Buch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - It is evident that a defective or deregulated complement system results in kidney diseases. An important role of complement effector and regulatory proteins in pathological settings of the kidney has been demonstrated. A large panel of distinct human kidn…ey diseases is caused by defective complement control. Genetic analyses have identified mutations in complement regulators that are associated with these diseases. Mutations have been identified in the fluid phase alternative pathway regulator Factor H and the membrane regulator Membrane Cofactor Protein MCP (CD46). The functional characterization of the mutant proteins allows to define the pathophysiological events on a molecular level. These new concepts and data on disease mechanisms allowed establishing new diagnostic and promising therapeutic approaches for several human kidney diseases. Molecular biology, clinics and therapy are discussed in this volume.
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Condition: New. It is evident that a defective or deregulated complement system results in kidney diseases. An important role of complement effector and regulatory proteins in pathological settings of the kidney has been demonstrated. This book discusses Molecular biology, clinics and therapy. Editor(s): Zipfel, Peter F. Series:… Progress in Inflammation Research. Num Pages: 252 pages, biography. BIC Classification: MFG; MJCM; MJR; MMFM; PSF. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 16. Weight in Grams: 603. . 2005. 2006th Edition. hardcover. . . . . Books ship from the US and Ireland.
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Language: English
Published by LAP LAMBERT Academic Publishing Jan 2021, 2021
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -We examined the expression of the three complement regulatory proteins on erythrocytes, neutrophils, lymphocytes and monocytes from pediatric patients and controls. The proportion of cells expressing the three complement regulatory…proteins varied between the cell types we examined, as did the levels of expression of the proteins.Similar to the findings from pediatric patients, there were lower proportion of erythrocytes expressing CD35, CD55 and CD59 in adult patients than in adult controls. In addition, there were lower proportion of CD59-positive neutrophils and CD35-, CD59-positive lymphocytes, and CD59-positive monocytes in adult patients than in adult controls. When looking at protein levels, we observed that the MFI of CD35-positive erythrocytes was significantly higher in adult patients than in the adult control, while CD59-positive neutrophils and monocytes was significantly lower in adult patients than in the adult controls.The findings so far showed that there was, at least to some extent, a correlation between the expression of the complement regulatory proteins and the presence or absence of the disease. 56 pp. Englisch.
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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Alhabibi et al AlshaymaaI am Dr. Alshaymaa Mohamed Alhabibi, Lecturer of Clinical Pathology Department at the Faculty of Medicine/ Al-Azhar University for Girls. I have been a lecturer for 4 years and I… participate in the academic te.
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Language: English
Published by LAP LAMBERT Academic Publishing Jan 2021, 2021
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Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -We examined the expression of the three complement regulatory proteins on erythrocytes, neutrophils, lymphocytes and monocytes from pediatric patients and controls. The proportion of cells expressing the three complement regulatory prot…eins varied between the cell types we examined, as did the levels of expression of the proteins.Similar to the findings from pediatric patients, there were lower proportion of erythrocytes expressing CD35, CD55 and CD59 in adult patients than in adult controls. In addition, there were lower proportion of CD59-positive neutrophils and CD35-, CD59-positive lymphocytes, and CD59-positive monocytes in adult patients than in adult controls. When looking at protein levels, we observed that the MFI of CD35-positive erythrocytes was significantly higher in adult patients than in the adult control, while CD59-positive neutrophils and monocytes was significantly lower in adult patients than in the adult controls.The findings so far showed that there was, at least to some extent, a correlation between the expression of the complement regulatory proteins and the presence or absence of the disease.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 56 pp. Englisch.
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Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - We examined the expression of the three complement regulatory proteins on erythrocytes, neutrophils, lymphocytes and monocytes from pediatric patients and controls. The proportion of cells expressing the three complement regulatory prote…ins varied between the cell types we examined, as did the levels of expression of the proteins.Similar to the findings from pediatric patients, there were lower proportion of erythrocytes expressing CD35, CD55 and CD59 in adult patients than in adult controls. In addition, there were lower proportion of CD59-positive neutrophils and CD35-, CD59-positive lymphocytes, and CD59-positive monocytes in adult patients than in adult controls. When looking at protein levels, we observed that the MFI of CD35-positive erythrocytes was significantly higher in adult patients than in the adult control, while CD59-positive neutrophils and monocytes was significantly lower in adult patients than in the adult controls.The findings so far showed that there was, at least to some extent, a correlation between the expression of the complement regulatory proteins and the presence or absence of the disease.
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Language: English
Published by Springer, Basel, Birkhäuser Basel, Birkhäuser Dez 2005, 2005
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Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -It is evident that a defective or deregulated complement system results in kidney diseases. An important role of complement effector and regulatory proteins in pathological settings of the kidney has been demonstrated. A large panel of dis…tinct human kidney diseases is caused by defective complement control. Genetic analyses have identified mutations in complement regulators that are associated with these diseases. Mutations have been identified in the fluid phase alternative pathway regulator Factor H and the membrane regulator Membrane Cofactor Protein MCP (CD46). The functional characterization of the mutant proteins allows to define the pathophysiological events on a molecular level. These new concepts and data on disease mechanisms allowed establishing new diagnostic and promising therapeutic approaches for several human kidney diseases. Molecular biology, clinics and therapy are discussed in this volume. 236 pp. Englisch.
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Gebunden. Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Role of genetic mutations in regulator proteinsNew therapies in human kidney diseasesProf. Zipfel is a well renowned scientist in this area of researchThe understanding how complement relates to glomerular d…iseaseshas evolved con.
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Buch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -It is evident that a defective or deregulated complement system results in kidney diseases. An important role of complement effector and regulatory proteins in pathological settings of the kidney has been demonstrated. A large panel of distinc…t human kidney diseases is caused by defective complement control. Genetic analyses have identified mutations in complement regulators that are associated with these diseases. Mutations have been identified in the fluid phase alternative pathway regulator Factor H and the membrane regulator Membrane Cofactor Protein MCP (CD46). The functional characterization of the mutant proteins allows to define the pathophysiological events on a molecular level. These new concepts and data on disease mechanisms allowed establishing new diagnostic and promising therapeutic approaches for several human kidney diseases. Molecular biology, clinics and therapy are discussed in this volume.Springer Nature c/o IBS, Benzstrasse 21, 48619 Heek 260 pp. Englisch.
