Dirsch Verena (215 results)

1st ed. 2022. IX, 106 p. Hardcover. Versand aus Deutschland / We dispatch from Germany via Air Mail. Einband bestoßen, daher Mängelexemplar gestempelt, sonst sehr guter Zustand. Imperfect copy due to slightly bumped cover, apart from this in very good condition. Stamped. Progress in the Chemistry of Organic Natural Products, 117. Sprache: Englisch.

Condition: New. In.

Condition: Brand New. New. US edition. Expediting shipping for all USA and Europe orders excluding PO Box. Excellent Customer Service.

Hardcover. Condition: new. Hardcover. This book describes a unique class of secondary metabolites, the mono- and dimeric-naphthylisoquinoline alkaloids. They exclusively occur in lianas of the palaeotropical Ancistrocladaceae and Dioncophyllaceae plant families. Their unprecedented structures include stereogenic centers and rotationally hindered, and therefore stereogenic, axes. Extended recent investigations on six Ancistrocladus species from Asia, as reported in this contribution, shed light on their fascinating phytochemical productivity, with over 100 intriguing natural products. This high chemodiversity arises from a similarly unique biosynthesis from acetate-malonate units, following a novel polyketidic pathway to plant-derived isoquinoline alkaloids. Some of the compounds show most promising anti-parasitic activities. Additionally, strategies for the regio- and stereoselective total synthesis of the alkaloids, including the directed construction of the chiral axis, are also presented. This book describes a unique class of secondary metabolites, the mono- and dimeric-naphthylisoquinoline alkaloids. This high chemodiversity arises from a similarly unique biosynthesis from acetate-malonate units, following a novel polyketidic pathway to plant-derived isoquinoline alkaloids. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.

Condition: Brand New. New. US edition. Expediting shipping for all USA and Europe orders excluding PO Box. Excellent Customer Service.

Condition: New. In.

Condition: Sehr gut. Zustand: Sehr gut | Sprache: Englisch | Produktart: Bücher | This volume begins with a short history of malaria and follows with a summary of its biology. It then traces the fascinating history of the discovery of quinine for malaria treatment, and then describes quinine¿s biosynthesis, its mechanism of action, and its clinical use, concluding with a discussion of synthetic antimalarial agents based on quinine¿s structure. It also covers the discovery of artemisinin and its development as the source of the most effective current antimalarial drug, including summaries of its synthesis and biosynthesis, its mechanism of action, and its clinical use and resistance. A short discussion of other clinically used antimalarial natural products leads to a detailed treatment of additional natural products with significant antiplasmodial activity, classified by compound type. Although the search for new antimalarial natural products from Nature¿s combinatorial library is challenging, it is very likely to yield new antimalarial drugs. This book thus ends byidentifying ten natural products with development potential as clinical antimalarial agents.

Condition: New.

hardcover. Condition: Fine.

Condition: New. In.

Condition: New. In.

Hardcover. Condition: new. Hardcover. The present volume is the third in a trilogy that documents naturally occurring organohalogen compounds, bringing the total number from fewer than 25 in 1968 to approximately 8,000 compounds to date. Nearly all of these natural products contain chlorine or bromine, with a few containing iodine and, fewer still, fluorine. Produced by ubiquitous marine (algae, sponges, corals, bryozoa, nudibranchs, fungi, bacteria) and terrestrial organisms (plants, fungi, bacteria, insects, higher animals) and universal abiotic processes (volcanos, forest fires, geothermal events), organohalogens pervade the global ecosystem. Newly identified extraterrestrial sources are also documented. In addition to chemical structures, biological activity, biohalogenation, biodegradation, natural function, and future outlook are presented. The present volume is the third in a trilogy that documents naturally occurring organohalogen compounds, bringing the total number from fewer than 25 in 1968 to approximately 8,000 compounds to date. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.

Condition: New. In.

Paperback. Condition: Brand New. 115 pages. 9.25x6.10x0.35 inches. In Stock.

Taschenbuch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - This volume begins with a short history of malaria and follows with a summary of its biology. It then traces the fascinating history of the discovery of quinine for malaria treatment, and then describes quinine's biosynthesis, its mechanism of action, and its clinical use, concluding with a discussion of synthetic antimalarial agents based on quinine's structure. It also covers the discovery of artemisinin and its development as the source of the most effective current antimalarial drug, including summaries of its synthesis and biosynthesis, its mechanism of action, and its clinical use and resistance. A short discussion of other clinically used antimalarial natural products leads to a detailed treatment of additional natural products with significant antiplasmodial activity, classified by compound type. Although the search for new antimalarial natural products from Nature's combinatorial library is challenging, it is very likely to yield new antimalarial drugs. This book thus ends byidentifying ten natural products with development potential as clinical antimalarial agents.

Condition: new.

Taschenbuch. Condition: Neu. Neuware -This volume begins with a short history of malaria and follows with a summary of its biology. It then traces the fascinating history of the discovery of quinine for malaria treatment, and then describes quinine¿s biosynthesis, its mechanism of action, and its clinical use, concluding with a discussion of synthetic antimalarial agents based on quinine¿s structure. It also covers the discovery of artemisinin and its development as the source of the most effective current antimalarial drug, including summaries of its synthesis and biosynthesis, its mechanism of action, and its clinical use and resistance. A short discussion of other clinically used antimalarial natural products leads to a detailed treatment of additional natural products with significant antiplasmodial activity, classified by compound type. Although the search for new antimalarial natural products from Nature¿s combinatorial library is challenging, it is very likely to yield new antimalarial drugs. This book thus ends byidentifying ten natural products with development potential as clinical antimalarial agents.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 120 pp. Englisch.

Condition: New.

Condition: New.

Hardcover. Condition: new. Hardcover. This book discusses the phytochemistry of bryophytes, with a particular focus on their biologically active natural products and their potential applications in medicine, cosmetics, and as foods. Bryophytes, which include the mosses, liverworts, and hornworts, produce a plethora of terpenoids, phenolic compounds, and polyketides that exhibit diverse pharmacological activities, including anti-inflammatory, antiobesity, antioxidant, cytotoxic, and muscle-relaxant effects. The volume also explores the characteristic odors and flavors of bryophytes, as well as their possible use in the cosmetics industry, as food additives, and ultimately as medicinal drugs. Additionally, the biosynthesis pathways and synthesis of selected bioactive bryophyte compounds are discussed, highlighting the potential of these fascinating and ancient plants as a source of novel and valuable natural products. This book discusses the phytochemistry of bryophytes, with a particular focus on their biologically active natural products and their potential applications in medicine, cosmetics, and as foods. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.

Condition: New.

Condition: New. 1st ed. 2022 edition NO-PA16APR2015-KAP.

Hardback. Condition: New. 2022 ed.

Condition: As New. Unread book in perfect condition.

Hardcover. Condition: new. Hardcover. This book describes a unique class of secondary metabolites, the mono- and dimeric-naphthylisoquinoline alkaloids. They exclusively occur in lianas of the palaeotropical Ancistrocladaceae and Dioncophyllaceae plant families. Their unprecedented structures include stereogenic centers and rotationally hindered, and therefore stereogenic, axes. Extended recent investigations on six Ancistrocladus species from Asia, as reported in this contribution, shed light on their fascinating phytochemical productivity, with over 100 intriguing natural products. This high chemodiversity arises from a similarly unique biosynthesis from acetate-malonate units, following a novel polyketidic pathway to plant-derived isoquinoline alkaloids. Some of the compounds show most promising anti-parasitic activities. Additionally, strategies for the regio- and stereoselective total synthesis of the alkaloids, including the directed construction of the chiral axis, are also presented. This book describes a unique class of secondary metabolites, the mono- and dimeric-naphthylisoquinoline alkaloids. This high chemodiversity arises from a similarly unique biosynthesis from acetate-malonate units, following a novel polyketidic pathway to plant-derived isoquinoline alkaloids. Shipping may be from our Sydney, NSW warehouse or from our UK or US warehouse, depending on stock availability.

Hardcover. Condition: new. Hardcover. This book presents recent reports of total syntheses involving a photocatalytic reaction as a key step in the methodology. Modern photocatalysis has proven its generality for the development and functionalization of native functionalities. To date, the field has found broad applications in diverse research areas, including the total synthesis of natural products. Among the selected examples presented in this book, it highlights how the photocatalytic process proceeds in a highly chemo-, regio-, and stereoselective manner, thereby allowing the rapid access to structurally complex architectures under light-driven conditions. This book presents recent reports of total syntheses involving a photocatalytic reaction as a key step in the methodology. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.

Condition: New.

Hardcover. Condition: new. Hardcover. This book deals with neurotrophins (NGF, BDNF, NT3, NT4), which can decrease cell death, induce differentiation, as well as sustain the structure and function of neurons. This makes neurotrophins potential therapeutic agents for the treatment of neurodegenerative disorders. However, these proteins have so far been ineffective in clinical trials mostly because they cannot pass the blood-brain barrier owing to their high-molecular weights. Consequently, small molecules that mimic neurotrophins and stimulate the synthesis of endogenous neurotrophins or enhance their neurotrophic actions are expected to be promising alternatives. Small-molecule natural products, which have been used in dietary functional foods or in traditional medicine over the course of human history, have potential to be developed as new therapeutic agents against neurodegenerative conditions such as Alzheimers disease. In this book, the authors introduce a variety of natural products possessing neurotrophic properties such as neurogenesis, neurite outgrowth promotion (neuritogenesis), and neuroprotection and focus on the chemistry and biology of several neurotrophic natural products. This book deals with neurotrophins (NGF, BDNF, NT3, NT4), which can decrease cell death, induce differentiation, as well as sustain the structure and function of neurons. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.

Condition: new.

Condition: New.